Immunopathology Section
Recent Publications
Selected Review Articles
C.C. Chan, Q. Li: Immunopathology of uveitis. Br J Ophthalmol 82:91-96, 1998. PubMed
G. Adamus, C.C. Chan: Experimental autoimmune uveitides: Multiple antigens, diverse diseases. In Caspi, R.R. (ed.): The eye: Immunity and autoimmunity. Int Rev Immunol 21:209-229, 2002. PubMed
C.C. Chan: Molecular pathology of primary intraocular lymphoma. Tranas Am Ophthalmol Soc 101:275-292, 2003. PubMed
J. Tuo, C.M. Bojanowski, C.C. Chan: Genetic factors of age-related macular degeneration. Prog Ret Eye Res 23:229-249, 2004. PubMed
M. Patel, C.C. Chan: Immunopathological aspects of age-related macular degeneration. Sem Immunopathol 30:97-110, 2008. PubMed
X. Ding, X. Ding, M. Patel, C.C. Chan: Molecular pathology of age-related macular degeneration. Prog Ret Eye Res 28:1-18, 2009. PubMed
H.L. Ramkumar, J. Zhang, C.C. Chan: Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD). Prog Ret Eye Res 29:169-190, 2010. PubMed
Y. Wang, V.M. Wang, C.C. Chan: The role of anti-inflammatory agents in age-related macular degeneration (AMD) treatment. Eye 25:127-139, 2011. PubMed
C.C. Chan, J.L. Rubenstwin, S.E. Coupland, J.L. Davis, J.W. Harbour, P.B. Johnston, N. Cassoux, V. Touitou, J.R. Smith, T.T. Batchelor, J.S. Pulido: Primary vitreoretinal lymphoma: A report from an international primary central nervous system lymphoma collaborative group symposium. The Oncologist 16:1589-1599, 2011. PubMed
Peer Reviewed Journal Articles
D. Shen, J. Tuo, M. Patel, A.A. Herzlich, X. Ding, E.Y. Chew, C.C. Chan: Chlamydia pneumoniae infection, complement factor H variants, and age-related macular degeneration. Br J Ophthalmol 93:405-408, 2009. PubMed
L. Cimino, C.C. Chan, D. Shen, L. Masini, F. Ilariucci, M. Masetti, S. Asioli, L. Cappuccini, A. Sartori: Ocular involvement in nasal natural killer T-cell lymphoma. Int Ophthalmol 29:275-279, 2009. PubMed
X. Ding, R.J. Bishop, A. A. Herzlich, M. Patel, C.C. Chan: Limbal stem cell deficiency arising from systemic chemotherapy with hydroxycarbamide. Cornea 28:221-223, 2009. PubMed
I.M. MacDonald, L. Russell, C.C. Chan: Choroideremia: New findings from ocular pathology and review of recent literature. Surv Ophthalmol 54:401-407, 2009. PubMed
G. Levy-Clarke, X. Ding, S. Yeh, S. Gangaputra, T. Goodglick, G. Byrnes, R.B. Nussenblatt, C.C. Chan: Recalcitrant granulomatous sclerouveitis in a patient with granulomatous ANCA associated vasculitis. Ocul Immunol Inflamm 17:83-87, 2009. PubMed
C.C. Chan, T.C. Sauer: Ocular imaging in primary retinal lymphoma. Am J Ophthalmol 147:764-765, 2009. PubMed
X. Cao, R.J. Bishop, F. Forooghian, Y. Cho, R.N. Fariss, C.C. Chan: Autoimmune retinopathy in systemic lupus erythematosus: Histopathologic features. Open Ophthalmol J 3:15-19, 2009. PubMed
J. Tuo, R.J. Ross, A.A. Herzlich, D. Shen, X. Ding, M. Zhou, S.L. Coon, N. Hussein, N. Salem, Jr., C.C. Chan: A high omega-3 fatty acid diet reduces retinal lesions in a murine model of macular degeneration. Am J Pathol 175:799-807, 2009. PubMed
S.E. Coupland, C.C. Chan, J.R. Smith: Pathophysiology of retinal lymphoma. Ocul Immunol Inflamm 17:227-237, 2009. PubMed
L.J. Faia, C.C. Chan: Primary intraocular lymphoma. Arch Pathol Lab Med 133:1228-1232, 2009. PubMed
A.R. Djalilian, J.Y. Kim, H.N. Saeed, E.J. Holland, C.C. Chan: Histopathology and treatment of corneal disease in keratitis, ichthyosis, and deafness (KID) syndrome. Eye 24:738-740, 2010. PubMed
A.A. Herzlich, X. Ding, D. Shen, R.J. Ross, J. Tuo, C.C. Chan: Peroxisome proliferator-activated receptor expression in murine models and humans with age-related macular degeneration. Open Biol J 2:141-148, 2009. PubMed
A. Lu, L. Ng, M. Ma, B. Kefas, T.F. Davies, Z. Hernandez, C.C. Chan, D. Forredest: Retarded developmental expression and patterning of retinal cone opsins in hypothyroid mice. Endocrinology 150:1536-1544, 2009. PubMed
X. Ding, M. Patel, A.A. Herzlich, P.C. Sieving, C.C. Chan: Ophthalmic pathology of Nance-Horan syndrome: Case report and review of the literature. Ophthalmic Genet 30:127-175, 2009. PubMed
X. Ding, M. Patel, D. Shen, A.A. Herzlich, X. Cao, R. Villasmil, K. Klupsch, J. Tuo, J. Downward, C.C. Chan: Enhanced HtrA2/Omi expression in oxidative injury to retinal pigment epithelial cells and murine models of neurodegeneration. Invest Ophthalmol Vis Sci 50:4957-4966, 2009. PubMed
C.C. Chan, S. Fisson, B. Bodaghi: The future of primary intraocular lymphoma (retinal lymphoma). Ocul Immunol Inflamm 17;375-379, 2009. PubMed
Y. Cho, J.J. Wang, E.Y. Chew, F.L. Ferris, III, P. Mitchell, C.C. Chan, J. Tuo: Toll-like receptor polymorphisms and age-related macular degeneration: replication in three case-control samples. Invest Ophthalmol Vis Sci 50:5614-5618, 2009. PubMed
T.C. Sauer, S.M. Meyers, D. Shen, S. Vegh, C. Vygantas, C.C. Chan: Primary intraocular (retinal) lymphoma following ocular toxoplasmosis. Retina Cases Brief Reports 4:160-163, 2010. PubMed
Y. Cho, F.R. Rickles, L.M. Parver, J. Tuo, C.C. Chan: The potential pathophysiological role of tissue factor in age-related macular degeneration. Exp Rev Ophthalmol 5:27-34, 2010.
S. Yeh, E.D. Weichel, L.J. Faia, T.A. Albini, K.K. Wroblewski, M. Stetler-Stevenson, P. Ruiz, H.N. Sen, C.C. Chan, R.B. Nussenblatt: 25-gauge transconjuctival sutureless vitrectomy for the diagnosis of intraocular lymphoma. Br J Ophthalmol 94:633-638, 2010. PubMed
X. Cao, M. Liu, J. Tuo, D. Shen, C.C. Chan: The effect of quercetin in cultured human RPE cells under oxidative stress and in Ccl2/Cx3cr1 double deficient mice. Exp Eye Res 91:15-25, 2010. PubMed
J. Tang, M.B. Rivers, A.A. Moshfeghi, H.W. Flynn, C.C. Chan: Pathology of Macular Foveoschisis Associated with Degenerative Myopia. J Ophthalmol 2010:1-4, 2010. PubMed
E. Furusato, J.D. Cameron, C.C. Chan: Evolution of cellular inclusions in Bietti’s crystalline dystrophy. Ophthalmol Eye Dis 2:9-15, 2010. PubMed
C.C. Chan: Couching for cataracts in China. Surv Ophthalmol 55:393-398, 2010. PubMed
M.M. Liu, J. Tuo, C.C. Chan: Gene therapy for ocular diseases. Br J Ophthalmol 95:604-612, 2011. PubMed
C.C. Chan, M.M. Liu, J.C. Tsai: The first Western style hospital in China. Arch Ophthalmol 129:791-797, 2011. PubMed
Y. Cho, X. Cao, D. Shen, J. Tuo, L.M. Parver, F.R. Rickles, C.C. Chan: Evidence for enhanced tissue factor expression in age-related macular degeneration. Lab Invest 91:591-526, 2011. PubMed
M.M. Liu, E. Furusato, X. Cao, D. Shen, C.C. Chan: Ocular manifestations and pathology of adult T-cell leukemia/lymphoma associated with human T-lymphotropic virus type 1 (HTLV-1). Rare Tumors 2:e63;179-182, 2010. PubMed
D. Shen, X. Cao, L. Zhao, J. Tuo, W.T. Wong, C.C. Chan: Naloxone ameliorates retinal lesions in Ccl2/Cx3cr1 double deficient mice via modulation of microglia. Invest Ophthalmol Vis Sci 52:2897-2904, 2011. PubMed
E. Furusato, D. Shen, X. Cao, B. Furusato, R.B. Nussenblatt, E.J. Rushing, C.C. Chan: Inflammatory cytokine and chemokine expression in sympathetic ophthalmia. Histol Histopathol 26:1145-1151, 2011. PubMed
M.M. Liu, E. Agron, E.Y. Chew, C.B. Melerle, F.L. Ferris, III, C.C. Chan, J. Tuo: Copy number variation in candidate genes in neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci 52:3129-3135, 2011. PubMed
J. Tuo, J.J. Pang, X. Cao, D. Shen, J. Zhang, A. Scaria, S.C. Wadsworth, P. Pechan, S.L. Boye, W.W. Hauswirth, C.C. Chan: AAV-5 mediated sFLT01 gene therapy arrests retinal lesions in Ccl2-/-/Cx3cr1-/- mice. Neurobiol Aging 33:433.e431-433.e410, 2011. PubMed
H.L. Ramkumar, B.P. Brooks, X. Cao, D. Tamura, J.J. DiGiovanna, K.H. Kraemer, C.C. Chan: Ophthalmic manifestations and histopathology of xeroderma pigmentosum: Two clinicopathological cases and review of the literature. Surv Ophthalmol 56:348-361, 2011. PubMed
D.N. Hu, M. Chen, D.Y. Zhang, F. Ye, S.A. McCormick, C.C. Chan: Interleukin-1β increases baseline expression and secretion of interleukin-6 by human uveal melanocytes in vitro via p38 MAPK/NF-κB pathway. Invest Ophthalmol Vis Sci 52:3767-3774, 2011. PubMed
X. Cao, R. Ursea, D. Shen, H.L. Ramkumar, C.C. Chan: Aberrant fibrosis induced by an intrastromal corneal ring: a case report. J Med Case Rep 5:398, 2011. PubMed
X. Cao, D. Shen, M.M. Patel, J. Tuo, T.M. Johnson, T.W. Olsen, C.C. Chan: Macrophage polarization in the maculare of age-related macular degeneration: a pilot study. Pathol Int 61:528-535, 2011. PubMed
F. Forooghian, A.B. Merkur, V. White, D. Shen, C.C. Chan: High-definition optical coherence tomography features of primary vitreoretinal lymphoma. Ophthal Surg Las Im 42:e97-99, 2011. PubMed
D. Ardeljan, J. Tuo, C.C. Chan: Carboxyethylpyrrole plasma biomarkers in age-related macular degeneration. Drug Future 36:713-718, 2011.
Y. Wang, D. Shen, V.M. Wang, H.N. Sen, C.C. Chan: Molecular biomarkers for the diagnosis of primary vitreoretinal lymphoma. Int J Mol Sci 12:5684-5697, 2011. PubMed
Supplemental Materials
C.C. Chan, J.A. Gonzales: Primary Intraocular Lymphoma. World Scientific Publishing Co., Singapore, London, Hackensack NJ, 2007. World Scientific
C. Cukras, C.C. Chan: Chapter IV. Diagnosis and treatment of retinitis pigmentosa based on the pathology. In Retinitis Pigmentosa: Causes, diagnosis and treatment. Nova Science Publisher, Hauppauge, NY 2010; pp.111-125. Nova Science Pub
H.E. Wiley, C.C. Chan: Chapter 1. Correlation of phenotype and genotype in age-related macular degeneration. In Macular degeneration: Causes, Diagnosis and Treatment. E.J. Campbell, L.M. McMarnn (eds). Nova Science Publisher, Hauppauge, NY 2011; pp. 1-28. Nova Science Pub
T.A. Larson, H.N. Sen, C.C. Chan: Chapter VI. Clinical and immunological highlights of non-infectious uveitis. In Advances in Eye Research. Volume 1. Nova Science Pulbisher, Hauppauge, NY 2011; pp. 131-146. Nova Science Pub
Last Reviewed: January 2012
