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Immunopathology Section

Ocular inflammatory models Ocular tumor model Genetic targeted models with ocular findings

Primary vitreoretinal lymphoma (PVRL)

Primary vitreoretinal lymphoma (PVRL) is a subset of primary CNS lymphoma. PVRL is mostly a diffuse large B cell non-Hodgkin's lymphoma that usually invades the retina, vitreous, or optic nerve with or without concomitant CNS involvement. Majority of PVRL is a diffuse large B cell lymphoma. Although it is a rare disease, PVRL is fatal and the incidence has increased in the past two decades. Our main interests are diagnosis, molecular pathology and pathogenesis of the malignancy.

Fundus photo showing primary vitreoretinal lymphoma
fundus photo showing primary intraocular lymphoma

Photomicrograph slide showing lymphoma between retinal and choroid
Photomicrograph slide showing lymphoma between retinal and choroid



Department of Health and Human Services NIH, the National Institutes of Health USA.gov