Immunopathology Section

• Current Research
• Staff
• Recent Publications

Current Research

Research activities and goals are divided into two main areas:

(1) Research on clinical specimens with the aims of sharpening diagnosis, understanding disease pathogenesis, and improving patient management: The focus is on two diseases, primary intraocular lymphoma and age-related macular degeneration.

• Primary intraocular lymphoma (PIOL)
• Age related macular degeneration (AMD)

(2) Research on model systems of experimental eye diseases: The goal here is to study different pathological conditions mimicking various human ocular diseases such as degeneration, inflammation, and neoplasm; and to evaluate the effects of new therapeutic agents on these models.

Genetic targeted ocular disease models

• Age-related retinal degeneration

Ocular tumor models

• Murine ocular lymphoma

Ocular inflammatory models

• Experimental autoimmune uveoretinitis (EAU)
• Endotoxin-induced uveitis (EIU)
• Experimental melanin protein-induced uveitis (EMIU)
• Murine acquired ocular toxoplasmosis
• Experimental blepharitis
• Murine allergic conjunctivitis

Staff

Name	Title	E-mail
Chi-Chao Chan, M.D.	Section Head	ccc@helix.nih.gov
Jingsheng Tuo, M.D., Ph.D.	Staff Scientist	TuoJ@nei.nih.gov
De Fen Shen, Ph.D.	Senior Biologist	dfshen@box-d.nih.gov
Xiaoyan Ding, M.D., Ph.D.	Post-Doctoral Fellow	dingyx@nei.nih.gov
Alexandra Herzlich, M.D.	NIH Medical Year-Off Trainee	herzlicha@nei.nih.gov
Theodor Sauer, B.S.	Post-Baccalaureate IRTA Fellow	sauert@nei.nih.gov
Mrinali Patel, B.S	HHMI-NIH Scholar	patelmm@mail.nih.gov
Mary Alice Crawford, B.A.	Senior Histologist	crawform@intra.nei.nih.gov
Maribel Santiago, B.S.	Histologist	santiagom@mail.nih.gov
Iris Miller Wise	Histologist	milleri@intra.nei.nih.gov
Ching Yim-Banzuelo	Contract Histologist	yimbanzueloc@nei.nih.gov