Immunopathology Section
Current Research
Research activities and goals are divided into two main areas:
(1) Research on clinical specimens with the aims of sharpening diagnosis, understanding disease pathogenesis, and improving patient management: The focus is on two diseases, primary intraocular lymphoma and age-related macular degeneration.
(2) Research on model systems of experimental eye diseases: The goal here is to study different pathological conditions mimicking various human ocular diseases such as degeneration, inflammation, and neoplasm; and to evaluate the effects of new therapeutic agents on these models.
Genetic targeted ocular disease models
Ocular tumor models
Ocular inflammatory models
- Experimental autoimmune uveoretinitis (EAU)
- Endotoxin-induced uveitis (EIU)
- Experimental melanin protein-induced uveitis (EMIU)
- Murine acquired ocular toxoplasmosis
- Experimental blepharitis
- Murine allergic conjunctivitis
Staff

Immunopathology: (left to right)Stanley Park, Defen Shen, Yujuan Wang, Chi-Chao Chan, Daniel Ardeljan, Mones Abu-Asab, Jingsheng Tuo.

Standing: Michelle Roof, Doretha Huntley, Hazel Lozano, Mones Abu-Asab, Janelle Coles, Iris Wise.
Sitting: Chi-Chao Chan
| Name | Title | |
|---|---|---|
Chi-Chao Chan, M.D.![]() |
Section Head | ccc@helix.nih.gov |
| Jingsheng Tuo, M.D., Ph.D. | Staff Scientist | TuoJ@nei.nih.gov |
| De Fen Shen, Ph.D. | Senior Biologist | dfshen@box-d.nih.gov |
| Yujuan Wang, M.D., Ph.D | Post-doctoral Fellow | yujuan.wang@nih.gov |
| Vinson Wang, B.S. | Special Volunteer | vinson.wang@nih.gov |
| Daniel Ardeljan, B.S. | Post-baccalaureate IRTA Fellow | daniel.ardeljan@nih.gov |
| Stanley Park, B.S. | NIH-HHMI Scholar | stanley.park@nih.gov |
| Histopathology Core | ||
| Chi-Cho Chan, M.D. | Head, Histology Core | chanc@nei.nih.gov |
| Iris Wise | Lead Histologist | milleri@intra.nei.nih.gov |
| Janelle Coles | Histologist | colesjs@mail.nih.gov |
| Michelle Roof | Histologist (part time) | roofm@mail.nih.gov |
| Doretha Huntley, HT | Histologist (part time) | huntleyde@mail.nih.gov |
| Mones Abu-Asab, Ph.D. | Biologist & Head, EM Core | mones@nei.nih.gov |
Last Reviewed: April 2012
