Immunopathology Section
Current Research
Research activities and goals are divided into two main areas:
(1) Research on clinical specimens with the aims of sharpening diagnosis, understanding disease pathogenesis, and improving patient management: The focus is on two diseases, primary vitreoretinal lymphoma and age-related macular degeneration.
(2) Research on model systems of experimental eye diseases: The goal here is to study different pathological conditions mimicking various human ocular diseases such as degeneration, inflammation, and neoplasm; and to evaluate the effects of new therapeutic agents on these models.
Genetic targeted ocular disease models
Ocular tumor models
Ocular inflammatory models
- Experimental autoimmune uveoretinitis (EAU)
- Endotoxin-induced uveitis (EIU)
- Experimental melanin protein-induced uveitis (EMIU)
- Murine acquired ocular toxoplasmosis
- Experimental blepharitis
- Murine allergic conjunctivitis
Staff
Immunopathology: Front row (from left to right) Xi Kathy Chu, Chi-Chao Chan, Yujuan Wang Back row (from left to right) Mones Abu-Asab, Alexander Ogilvy, Jingsheng Tuo, Defen Shen.
Histopathology Core: (Sitting) Chi-Chao Chan. (Standing, left to right) Michelle Roof, Doretha Huntely, Alexander Ogilvy, Mones Abu-Asab, Janelle Coles, Iris Wise.
| Name | Title | |
|---|---|---|
Chi-Chao Chan, M.D. |
Section Head | ccc@helix.nih.gov |
| Jingsheng Tuo, M.D., Ph.D. | Staff Scientist | TuoJ@nei.nih.gov |
| De Fen Shen, Ph.D. | Senior Biologist | dfshen@box-d.nih.gov |
| Yujuan Wang, M.D., Ph.D | Post-doctoral Fellow | yujuan.wang@nih.gov |
| Vinson Wang, B.S. | Special Volunteer | vinson.wang@nih.gov |
| Daniel Ardeljan, B.S. | Special Volunteer | daniel.ardeljan@nih.gov |
| Xi (Kathy) Chu, B.A | Post-baccalaureate IRTA Fellow | kathy.chu@nih.gov |
| Histopathology Core | ||
| Chi-Chao Chan, M.D. | Head, Histology Core | chanc@nei.nih.gov |
| Iris Wise | Lead Histologist | milleri@intra.nei.nih.gov |
| Janelle Coles | Histologist | colesjs@mail.nih.gov |
| Michelle Roof | Histologist (part time) | roofm@mail.nih.gov |
| Doretha Huntley, HT | Histologist (part time) | huntleyde@mail.nih.gov |
| Mones Abu-Asab, Ph.D. | Biologist & Head, EM Core | mones@nei.nih.gov |
| Alexander Ogilvy, B.S. | Post-baccalaureate IRTA Fellow | alexander.ogilvy@nih.gov |
Last Updated: August 2012
