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National Eye Institute Intramural Research Day

National Institutes of Health, Building 60 (The Cloister)
1:00 to 4:30 PM

CONTENTS:

Program
Speakers
Poster Presentations
Organizing Committee

The purpose of this event is to provide an informal venue for the NEI intramural scientists to exchange scientific information and to promote communication and collaborations among the various laboratories in the intramural NEI program.

People viewing posters and talking with researchers

Program

12:30 - 1:00 P.M. Poster set up 1:00 - 2:15 P.M. Oral presentations 2:15 - 3:45 P.M. Posters, refreshments and snacks 3:45 - 4:30 P.M. General discussion and closing remarks

Speakers

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Martin Lizak Charles Egwuagu and Michele A. Basso Patricia Becerra

Michele A. Basso (mab@lsr.nei.nih.gov)

"Saccade Target Probability Modulates Neuronal Activity"
Michele A. Basso and Robert H. Wurtz
Section on Visual Motor Integration, Laboratory of Sensorimotor Research, NEI

Graeme Wistow (graeme@helix.nih.gov) "NEIBANK: EST analysis of Human Eye cDNA Libraries"
Graeme Wistow1, Steven Bernstein2, Don Smith1, Amita Behal1
1Section on Molecular Structure and Function, NEI
2University Of Maryland School of Medicine (SB)

Martin Lizak (LizakM@intra.nei.nih.gov) "Imaging the Human Eye in vivo with Magnetization Transfer Contrast"
Martin Lizak1, Manuel Datiles2, Anthony Aletras3, Peter Kador1, Robert Balaban3
1Laboratory of Ocular Therapeutics, NEI
2Ocular Genetics and Clinical Services Branch, NEI
3Laboratory of Cardiac Energetics, NHLBI

Patricia Becerra (pbecerra@helix.nih.gov) "Structure-function Relationships of Pigment Epithelium-derived Factor"
Patricia Becerra
Laboratory of Retinal Cell and Molecular Biology, NEI

Poster Presentations

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Rajeev Argarwal and Steve Kim
Rajeev K. Agarwal (ragarwal@helix.nih.gov) Title: Retroviral Gene Therapy of Experimental Autoimmune Uveitis (EAU)
Authors: Rajeev K. Agarwal1, Yubin Kang3, Elias Zambidis3, David W. Scott4, Chi-Chao Chan2, Rachel R. Caspi1
1Section on Immunoregulation, Laboratory of Immunology, NEI
2Section of Immunopathology, Laboratory of Immunology, NEI
3Department of Immunology, Holland Lab, American Red Cross, Rockville, MD

Marisol Aymerich (aymericm@intra.nei.nih.gov) Title: Binding of the Neurotrophic Factor Pigment Epithelium-Derived Factor (PEDF) to Bovine Retina
Authors: Maria S. Aymerich, Elena Alberdi, S. Patricia Becerra
Laboratory of Retinal Cell and Molecular Biology, NEI

Judit Baffi Title: A New Animal Model of Subretinal Neovascularization
Authors: Judit Baffi1, Gordon Byrnes1, Chi-Chao Chan2, Karl G. Csaky1
1Ocular Gene Therapy Section, Laboratory of Immunology, NEI
2Section of Immunopathology, Laboratory of Immunology, NEI

Rachel R. Caspi (rcaspi@helix.nih.gov) Title: Extraocular Expression of IRBP Induces Tolerance and Reduces Susceptibility to Experimental Autoimmune Uveoretinitis
Authors:Hui Xu1, Eric F. Wawrousek2, T. Michael Redmond3, Barbara Wiggert1, Chi-Chao Chan1, Rachel R. Caspi1, John M. Nickerson4
1Laboratory of Immunology, NEI
2Laboratory of Molecular and Developmental Biology, NEI
3Laboratory of Retinal Cell and Molecular Biology, NEI
4Ophthalmology Department, Emory University, Atlanta, Georgia

Christine M. Colvis (colvisc@intra.nei.nih.gov) Title:Characterization of a Novel Form of alpha B-crystallin from Human Cataracts
Authors: Christine M. Colvis1, Jose Jimenez1, Maria Moroni1, Yvonne Duglas-Tabor1, Jeffery A. Kowalak2, Donita L. Garland1
1Protein Biochemistry Section, Laboratory of Mechanisms of Ocular Diseases, NEI
2NICHD

Giesela Velez and Judit Baffi Marisol Aymerich and Ana Chepelinsky

Tom Creaven (CreavenT@intra.nei.nih.gov) Title: Development of a Mouse Corneal Cell Line that Can Be Induced to Differentiate
Authors:Tom Creaven, Alisa Kim, Todd Kays, Jenny Davis, Joram Piatigorsky
Section on Molecular Genetics, Laboratory of Molecular and Developmental Biology, NEI

Qiufang Cheng (qiufangc@intra.nei.nih.gov) Title: High Level Expression of Ferritin Light Chain mRNA in Lens Detected by Gene Arrays
Authors: Qiufang Cheng, Pedro Gonzalez, J. Samuel Zigler, Jr.
Lens and Cataract Biology Section, Laboratory of Molecular and Ocular Diseases, NEI

Yvonne Duglas-Tabor Title: Lens 2-D Gel Patterns
Authors: Yvonne Duglas-Tabor, Donita Garland
Protein Biochemistry Section, Laboratory of Mechanisms of Ocular Diseases, NEI

Gail Hollowell (holloweg@intra.nei.nih.gov) Title: Expression of the Transcription Factor AP-2alpha in the Lens
Authors: Gail Hollowell, Chiaki Ohtaka-Maruyama, Ana B. Chepelinsky
Regulation of Gene Expression Section, Laboratory of Molecular and Developmental Biology, NEI

Barry Hough (HoughB@intra.nei.nih.gov) Title: The Transcriptional Regulation of Two Crystallin Genes in the Lens and Cornea
Authors: R. Barry Hough, Joram Piatigorsky
Section on Molecular Genetics, Laboratory of Molecular and Developmental Biology, NEI

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Michael Kennedy (KennedyM@intra.nei.nih.gov) Title:Thymic Medullary Cells Express Retinal Specific Antigens
Authors: Michael C. Kennedy, Monique P. Gelderman, Igal Gery
Experimental Immunology Section, Laboratory of Immunology, NEI

Yong Sok Lee (yongslee@helix.nih.gov) Title: Molecular Dynamics Simulations of Tight Binding Inhibitor Tolrestat at the Active Site of Aldose Reductase
Authors:Yong S. Lee, Katsumi Sugiyama, Peter F. Kador
Laboratory of Ocular Therapeutics, NEI

Ernesto F. Moreira (ernesto@helix.nih.gov) Title:Cloning of a Retina-specific Oxysterol Binding Protein (OSBP2)
Authors: Ernesto F. Moreira, Cynthia J. Jaworski, Jung Wha Lee, Ignacio R. Rodriguez
Section on Gene Regulation, Laboratory of Retinal Cell and Molecular Biology, NEI

Cynthia J. Jaworski (jaworski@ncifcrf.nih.gov) Title: Bioinformatics and Data Mining Reveal a Multi-gene Family of Oxysterol Binding Proteins
Authors: Cynthia J. Jaworski, Ernesto F. Moreira, Jung Wha Lee, Ignacio R. Rodriguez
Section on Gene Regulation, Laboratory of Retinal Cell and Molecular Biology, NEI

William Samuel and Ernesto Moreira Dawn Richiert and Deborah Carper

Dawn Richiert Title: Lens protein changes during cataract formation and aging.
Authors: Dawn Richiert1, Santa Tumminia1, Ken Mitton1, Yvonne Duglas-Tabor2, Donna Garland2, Paul Russell1
1Aging and Ocular Disease Section, Laboratory of Mechanisms of Ocular Diseases, NEI
2Protein Biochemistry Section, Laboratory of Mechanisms of Ocular Diseases, NEI

Paul Russell (prvs@helix.nih.gov) Title: Tigr Tales: Finding Myocilin in the Human Eye
Authors: Paul Russell, Anastasia Karali, Fritz Stefani, Ernst Tamm
Section on Aging and Ocular Disease, Laboratory of Molecular and Ocular Diseases, NEI

William Samuel (william@helix.nih.gov) Title: Expression of Retinoid Receptors, RARa and RXRa, IN ARPE-19 Human Retinal Pigment Epithelial Cells
Authors: William Samuel, R. Krishnan Kutty, Geetha Kutty, Todd Duncan, Barbara Wiggert
Laboratory of Retinal Cell and Molecular Biology, NEI

Yuri Sergeev (sv2k@nih.gov) Title: Monomer-dimer equilibrium of normal and amino-terminal truncated mouse betaA3-crystallins
Authors: Yuri V. Sergeev, Paul T. Wingfield, J.Fielding Hejtmancik
Ophthalmic Molecular Genetics Section, Ophthalmic Genetics and Clinical Services Branch, NEI

Jen-Yue Tsai (Jtsai@helix.nih.gov) Title: Retinal Pericytes and Diabetic Retinopathy
Authors: Sanai Sato, Jen-Yue Tsai
Laboratory of Ocular Therapeutics, NEI

Meifen Zhang (Zhangm@intra.nei.nih.gov) Title: Immunologic and Pathogenic Profiles Of Double Transgenic Mice Expressing a Foreign Antigen in Their Eyes and Thymus; and Receptor Against it on Their T-Lymphocytes
Authors: Meifen Zhang1, Barbara Vistica1, Monique Gelderman1, Erik Wawrousek2, Ingal Gery1
1Experimental Immunology Section, Laboratory of Immunology, NEI
2Laboratory of Molecular Biology, NEI

Peggy Zelenka (Zelenka@helix.nih.gov) Title: 12(S)HETE regulates lens epithelial cell growth by enabling PKC activation
Authors: M.S. Reza Haque, Jaspreet A. Arora, Peggy S. Zelenka
Section on Cellular Differentiation, Laboratory of Molecular and Developmental Biology, NEI

Organizing Committee:

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Debbie Carper
Ana B. Chepelinsky
Christine Colvis
Tom Creaven
Charles Egwuagu
Bob Wheelock

Yvonne Duglas-Tabor


Department of Health and Human Services NIH, the National Institutes of Health USA.gov