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Cytokines, Immunity and Ocular Disease

The 3rd National Eye Institute/Laboratory of Immunology Alumni Conference

A Symposium in Honor of Dr. Igal Gery

September 19 and 20, 2002

Building 60
National Institutes of Health
Bethesda, Maryland

A Continuing Medical Education Conference Presented by the Laboratory of Immunology, National Eye Institute,
National Institutes of Health

On this page:

Introduction
Course Objectives
Continuing Education Credits
Scientific Program
Faculty
Hotel Information

Introduction

The Laboratory of Immunology of the National Eye Institute at the National Institutes of Health is pleased to announce its third alumni meeting, a symposium entitled "Cytokine, Immunity and Ocular disease." The symposium is a continuing medical educational conference, to be held on Thursday and Friday, September 19 and 20, in Building 60 of the National Institutes of Health in Bethesda, MD. The symposium has invited several world-leading immunologists and is open to everyone at the NIH. The NEI/LI Alumni Association has over 150 members, many of whom are leading national and international ophthalmologists and scientists in the field of ocular immunology and inflammation. The conference will facilitate scientific exchange and clinical case discussion among the audience and LI alumni members.

Course Objectives

This conference is intended for ophthalmologists, immunologists, internists, and other health care professionals who care for patients with ocular diseases, in particular, uveitis. Learning objectives for the conference include:

The participants will receive the most up-to-date information concerning the status of basic immunology, ocular immunology and uveitis.
The participants will be familiarized with fundamental immunology and its application in clinical practice.
The participants will understand the molecular basis for the clinical findings of autoimmune uveitis, inflammation, infection, and neovascularization.
The participants will discuss the scope of management in ocular inflammatory and other diseases, in particular, Behcet's syndromes, viral infections, and age-related macular degeneration.
The participants will identify the need for referrals to various specialists and sub-specialists when indicated.

Continuing Education Credits

The National Institutes of Health/Foundation for Advanced Education in the Sciences is accredited by the Accreditation Council for Continuing Medical Education to sponsor continuing medical education for physicians.

The National Institutes of Health/Foundation for Advanced Education in the Sciences designates this educational activity for a maximum of 10 hours in Category 1 credit towards the AMA Physician's Recognition Award. Each physician should claim only those hours of credit that he/she actually spent in the educational activity.

Scientific Program

Thursday, September 19

08:45 - 08:50 a.m.
Welcome
Robert B. Nussenblatt, M.D.

08:50 - 08:55
Opening Remarks
Paul A. Sieving, M.D., Ph.D.

08:55 - 09:00
Introduction Remarks
Byron H. Waksman, M.D.

09:00 - 10:30
Session I
Chair: Byron H. Waksman, M.D.

09:00 - 09:30
Joost J. Oppenheim, M.D.
From Interleukin 1 to Chemokines to Autoantigens in Uveitis

09:30 - 10:00
Nancy H. Ruddle, Ph.D.
Inflammation and Antigen Presentation in the Central Nervous System

10:00 - 10:30
Rachel R. Caspi, Ph.D.
Central and Peripheral Tolerance to Retinal Antigens

10:30 - 10:50 a.m.
Coffee Break

10:50 - 12:20 p.m.
Session II
Chair: Stephen I. Katz, M.D., Ph.D.

10:50 - 11:20
David W. Scott, Ph.D.
From Rat Spleens to Gene Therapy: Progress for Specific Tolerance in Autoimmune Diseases

11:20 - 11:50
Sharon M. Wahl, Ph.D.
TGF-beta: Reining in the Immune Response

11:50 - 12:20
Charles E. Egwuagu, Ph.D.
Putting SOCS in Th1/Th2 Lymphocyte Differentiation

12:20 - 1:30
Lunch

1:30 - 3:00
Session III
Chair: Rachel R. Caspi, Ph.D.

1:30 - 2:00
Stephen I. Katz, M.D., Ph.D.
Mechanisms Involved in Cell-Mediated Immunity in Skin

2:00 - 2:30
James T. Rosenbaum, M.D.
Using the Eye to Image the Immune Response

2:30 - 3:00
Karl G. Csaky, M.D., Ph.D.
The Role of Inflammation in Age-Related Macular Degeneration

3:00 - 3:20
Coffee Break

3:20 - 4:45
Session IV
Chair: Robert B. Nussenblatt

3:20 - 3:50
David BenEzra, M.D., Ph.D.
Cytokines and Ocular Angiogenesis

3:50 - 4:20
Janet L. Davis, M.D.
Ocular Fluids as Material for Research in Uveitis

4:20 - 4:50
Manabu Mochizuki, M.D., Ph.D.
HTLV-1 Uveitis

Friday, September 20

9:00 - 10:30 a.m.
Session I
Chair: David BenEzra/Janine A. Smith

9:00 - 09:15
Robert B. Nussenblatt, M.D.
Receptor directed therapy for ocular inflammatory disease

9:15 - 9:30
Scott M. Whitcup, M.D.
Drug Development in the 21st Century

9:30 - 9:45
Merih B. Soylu, M.D.
Behcet Disease in Southern Turkey

9:45 -10:00
Daniel F. Martin, M.D.
Update on CMV Retinitis

10:00 - 10:15
Grace Levy-Clarke, M.D.
The New Biologic and Immunosuppressive Agents Used by Rheumatologists and Their Implications for the Treatment of Uveitis- Scientific and Economic Considerations

10:15 - 10:30
Ronald R. Buggage, M.D.
Ocular Manifestations of HTLV-1 in Patients of American Descent

10:30 - 10:50 a.m.
Coffee Break

10:50 - 12:20 p.m.
Session II
Chair: Manabu Mochizuki/Ronald R. Buggage

10:50 - 11:05
Janine A. Smith, M.D.
Premature Ovarian Failure and Ocular Surface Disease

11:05 - 11:20
Ali Djalilian, M.D.
Limbal Stem Cell Transplantation

11:20 - 11:35
Gregory M. Fox, M.D.
Intraocular Biopsy for Diagnosis in Patients with Inflammatory Disease

11:35 - 11:50
Michael R. Robinson, M.D.
Wegener's Granulomatosis: A Review of the NEI Experience over Three Decades

11:50 - 12:05
David G. Callanan, M.D.
Intraocular Treatment for Primary CNS Lymphoma

12:05 - 12:20
Chi-Chao Chan, M.D.
>Expression of Chemokines and Chemokines Receptors in Uveitis and Primary Intraocular Lymphoma

12:20 - 12:30 p.m.
Summary and Adjourn
Robert B. Nussenblatt, M.D.

Faculty

David BenEzra, M.D., Ph.D.
Professor, Department of Ophthalmology
Hadassah University
Jerusalem
Israel

Ronald R. Buggage, M.D.
Director, Uveitis Fellowship
Laboratory of Immunology
National Eye Institute
National Institutes of Health

Karl G. Csaky, M.D., Ph.D.
Chief, Section of Gene Therapy
National Eye Institute
National institutes of Health

David G. Callanan, M.D.
Clinical Assistant Professor
Department of Ophthalmology
University of Texas Southwestern Medical School

Rachel R. Caspi, Ph.D.
Chief, Section of Immunoregulation
Laboratory of Immunology
National Eye Institute
National Institutes of Health

Chi-Chao Chan, M.D.
Chief, Section of immunopathology
Laboratory of Immunology
National Eye Institute
National Institutes of Health

Janet L. Davis, M.D.
Professor, Department of Ophthalmology
Bascom Palmer Eye Institute
University of Miami School of Medicine

Charles E. Egwuagu, Ph.D.
Chief, Section of molecular Immunology
Laboratory of Immunology
National Eye Institute
National Institutes of Health

Gregory M. Fox, M.D.
Kansas City, MO

Stephen I. Katz, M.D., Ph.D.
Director, National Institute of Arthritis and Musculoskeletal and Skin Diseases
National Institutes of Health

Grace Levy-Clark, M.D.
Sharp Rees-Stealy Medical Center
San Diego, CA

Daniel F. Martin, M.D.
Associate Professor
Department of Ophthalmology
Emory University School of Medicine

Manabu Mochizuki, M.D., Ph.D.
Professor and Chairman, Department of Ophthalmology
Tokyo Medical and Dental University School of Medicine
Tokyo
Japan

Robert B. Nussenblatt, M.D.
Chief, Laboratory of Immunology
National Eye Institute
National Institutes of Health

Joost J. Oppenheim, M.D.
Chief, Laboratory of Molecular Immunoregulation
National Cancer Institute
National Institutes of Health

Michael R. Robinson, M.D.
Chief, Consult Services Section
National Eye Institute
National Institutes of Health

James T.Rosenbaum, M.D.
Professor, Department of Ophthalmology
Casey Eye Institute
Oregon Health Sciences University

Nancy H. Ruddle, Ph.D.
Professor, Department of Epidemiology and Public Health and Section of Immunobiology
Yale University

David W. Scott, Ph.D.
Head, Immunology Department
Holland Laboratory
American Red Cross

Janine A. Smith, M.D.
Deputy Clinical Director
National Eye Institute
National Institutes of Health

Merih B. Soylu, M.D.
Professor, Department of Ophthalmology
Çukurova University Medical Faculty
Adana
Turkey

Sharon M. Wahl, Ph.D.
Chief, Oral Infection and Immunity Branch
National Institute of Dental and Craniofacial Research
National Institutes of Health

Byron H. Waksman, M.D.
Vice President
Waksman Foundation for Microbiology

Scott M. Whitcup, M.D.
Vice President
Allergan

Hotel Information

We have reserved a block of rooms at the rate of $150.00 per night. Please contact:

Bethesda Marriott
5151 Pooks Hill Road
Bethesda, MD 20814
301-897-9400
1-800-228-9290

For additional information about the Symposium, please contact:

Joe Razza
NEI Laboratory of Immunology
(301) 496-3123