Mechanisms of Retinoid and Lipid Metabolism in the Retina

A postdoctoral position is available immediately to study retinoid metabolic enzymes in the retina and their role in inherited blindness. The position is in the Laboratory of Retinal Cell & Molecular Biology (LRCMB, Molecular Mechanisms Section), National Eye Institute (NEI), National Institutes of Health (NIH), in Bethesda, MD. The section investigates aspects of vitamin A metabolism essential to vision, such as the role of the retinal pigment epithelium protein RPE65 in chromophore regeneration. We are investigating the structure/function and enzymatic mechanism of RPE65, developing mouse models to more closely parallel the spectrum of RPE65-related retinal dystrophies, and studying RPE65 gene regulation in the RPE. The successful candidate will participate in mechanistic/structure/functional studies of RPE65 and related enzymes to explore their roles in retinoid metabolism, and will receive training in a wide variety of research techniques in molecular biology, biochemistry, protein structure and/or mouse molecular genetics. For more information, see www.nei.nih.gov/intramural/mol_mech_sec.asp.

Applicants must have a Ph.D. and/or M.D., and a strong background in biochemistry, molecular biology and/or chemistry and less than 5 years of postdoctoral experience.

To apply, please send an email to the address below and include a cover letter explaining your interest in the position and your long-term career goals, CV, and the names and telephone numbers, postal and e-mail addresses of three references. Or send the above to:

T. Michael Redmond, Ph.D.
Senior Investigator
NEI-LRCMB, NIH
Bldg 6, Rm 117A
6 CENTER DR MSC 0608
BETHESDA, MD 20892-0608
Tel: (301) 496-0439
Fax: (301) 402-1883

The NIH is dedicated to building a diverse community in its training and employment programs. DHHS, NIH, and NEI are Equal Opportunity Employers.

Last Updated: May 2013