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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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As novel sights become familiar, different brain rhythms, neurons take over

A new study by researchers at MIT’s Picower Institute for Learning and Memory substantially advances understanding of how a mammalian brain enables “visual recognition memory.”
A mug of coffee

High caffeine consumption may be associated with increased risk of blinding eye disease

Consuming large amounts of daily caffeine may increase the risk of glaucoma more than three-fold for those with a genetic predisposition to higher eye pressure according to an international, multi-center study.
Eye diagram showing the uvea, optic nerve, retina, sclera, cornea and pupil.

International coalition classifies 25 subtypes of uveitis, an inflammatory eye disease

An international coalition of eye researchers used machine learning to develop classification criteria for 25 of the most common types of uveitis, a collection of over 30 diseases characterized by inflammation inside the eye.
Image of brain cells with "sparks" of red and yellow

Brain tumors caused by normal neuron activity in mice predisposed to such tumors

A study by researchers at Washington University School of Medicine in St. Louis and Stanford University School of Medicine shows that the normal day-to-day activity of neurons can drive the formation and growth of brain tumors.

Vision researchers at Wayne State discover new therapy to treat eye infections

Researchers at the Wayne State University School of Medicine have discovered that a metabolite called itaconate produced during cellular metabolism plays a role in protecting the eye from abnormal inflammation during infection.
Slice of OCT image hovers over 3D segmentation of retinal cells

AI Spots Individual Neurons in the Eye Better than Human Experts

A new combination of optical coherence tomography (OCT), adaptive optics and deep neural networks should enable better diagnosis and monitoring for neuron-damaging eye and brain diseases like glaucoma.
Traffic

New research assesses naturalistic driving techniques to link vision impairment and traffic accidents

New research from the University of Alabama at Birmingham has used naturalistic driving techniques to link vision impairment in older drivers to at-fault crashes and near-crashes.
city street at night as seen by a person with normal vision

A new theory for what’s happening in the brain when something looks familiar

University of Pennsylvania researchers propose a new theory for how the brain understands the level of activation expected from a sensory input and corrects for it, leaving behind the signal for familiarity.

Neural Implant Monitors Multiple Brain Areas at Once, Provides New Neuroscience Insights

Researchers at UCSD have developed a neural implant that monitors the activity of different parts of the brain at the same time, from the surface to deep structures.
Photoreceptor precursor cells (red) are shown with extended axons toward bipolar cells.

Audacious projects develop imaging technology to aid eye tissue regeneration

As regenerative therapies for blinding diseases move closer to clinical trials, the NEI's functional imaging consortium is pioneering noninvasive technologies to monitor the function of the retina’s neurons and their connections to the brain.