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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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National Eye Institute

Systemic therapy outperforms intraocular implant for treating uveitis

Systemic therapy consisting of corticosteroids and immunosuppressants preserved vision of uveitis patients better – and had fewer adverse outcomes – than a long-lasting corticosteroid intraocular implant, according to a clinical trial funded by NEI.
Grantee News

Preschool Children Face Increasing Vision Problems Over Coming Decades According to USC Roski Eye Institute Research Article in JAMA Ophthalmology

NEI funded research experts at the University of Southern California Roski Eye Institute found that visual impairment in preschool children will increase 26 percent affecting almost 220,000 children over the next 45 years.
blueprint eye

NIH launches competition to develop human eye tissue in a dish

The National Eye Institute (NEI), part of the National Institutes of Health, has opened the first stage of a federal prize competition designed to generate miniature, lab-grown human retinas.
Artist's rendering of photoreceptor signaling a retinal ganglion cell

Moving future regenerative therapies for blinding eye diseases to the clinic

A new report outlines steps to bringing future regenerative therapies for blinding diseases of the retina to patients. The retina is the light-sensitive tissue in the back of the eye. When stimulated, retinal neurons send visual information to the brain.
Infocard

NEI’s Healthy Vision Month 2017 puts spotlight on women

May is Healthy Vision Month when the National Eye Institute (NEI) encourages everyone to make eye health a priority.
Corneal section from a person with Fuchs dystrophy shows the presence of ATP1B1 in the corneal endothelium.

NIH-funded team identifies genetic underpinnings of Fuchs dystrophy

An international study of more than 5,417 people helps pinpoint the genetic risk factors associated with Fuchs endothelial corneal dystrophy, the most common disorder requiring corneal transplantation.
Eye

Helping the retina regenerate

A new report gives recommendations for regenerating retinal ganglion cells (RGCs), crucial neurons in the back of the eye that carry visual information to the brain.

NIH-Funded Scientists Home in on Molecular Causes of Secondary Cataract

Four to 12 percent of people undergoing cataract surgery to replace a cloudy lens with a clear artificial one develop posterior capsule opacification (PCO).
Image of a mouse retina

NIH scientists deploy CRISPR to preserve photoreceptors in mice

Silencing a gene called Nrl in mice prevents the loss of cells from degenerative diseases of the retina, according to a new study. The findings could lead to novel therapies for preventing vision loss from human diseases such as retinitis pigmentosa.
Xu Wang with Wai Wong in lab

Breast cancer drug dampens immune response, protecting light-sensing cells of the eye

The breast cancer drug tamoxifen appears to protect light-sensitive cells in the eye from degeneration, according to a new study in mice.

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