NEI Research News

Gene therapy for Leber congenital amaurosis (LCA), an inherited disorder that causes vision loss starting in childhood, improved patients’ eyesight and the sensitivity of the retina within weeks of treatment.

Five bold projects will develop new technology to noninvasively image cells of the eye in unprecedented detail.The National Eye Institute (NEI) announced the awards as part of its Audacious Goals Initiative.

The National Eye Institute (NEI) recently launched the first-ever human gene therapy trial for the vision disorder X-linked retinoschisis (XLRS). Researchers are conducting the trial at the National Institutes of Health Clinical Research Center in...

A class of medications long used to curb HIV infection shows promise as a therapy for age-related macular degeneration (AMD), suggest findings from an NIH-funded study.

New study suggests that neurons in the developing brains of mice are guided by a simple but elegant birth order rule that allows them to find and form their proper connections.

Researchers at the National Institutes of Health have developed a technique that will speed up the production of stem-cell derived tissues.

In laboratory tests, researchers have used electrical stimulation of retinal cells to produce the same patterns of activity that occur when the retina sees a moving object.

Researchers at the National Eye Institute (NEI) have described the functions of a gene responsible for anchoring cilia — sensory hair-like extensions present on almost every cell of the body.

Using a type of human stem cell, researchers have created a three-dimensional complement of human retinal tissue in the laboratory, which notably includes functioning photoreceptor cells capable of responding to light

A type of retina cell plays a more critical role in vision than previously known, a team led by Johns Hopkins University researchers has discovered.