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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Early visual experience drives precise alignment of cortical networks critical for binocular vision

Researchers at the Max Planck Florida Institute for Neuroscience identify three distinct cortical representations that develop independent of visual experience but undergo experience-dependent reshaping, an essential part of cortical network maturation.
Fluorescent images of mouse retinal layers

Retinal Texture Could Provide Early Biomarker Of Alzheimer’s Disease

Biomedical engineers at Duke University have devised a new imaging device capable of measuring the various layers of the retina at the back of the eye, which could be used to detect Alzheimer's disease.
Purple, pink, white rings showing fluorescence from retina section

Eyes send an unexpected signal to the brain

New research, led by Northwestern University, has found that a subset of retinal neurons sends inhibitory signals to the brain. Before, researchers believed the eye only sends excitatory signals.
diagram of the eye

Temple Scientists Regenerate Neurons in Mice with Spinal Cord Injury and Optic Nerve Damage

New research by scientists at the Lewis Katz School of Medicine Temple University (LKSOM) shows that gains in functional recovery from optic nerve injuries may be possible, thanks to a molecule known as Lin28, which regulates cell growth.
DNA methylation process

NEI researchers link age-related DNA modifications to susceptibility to eye disease

National Eye Institute (NEI) researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression.
Grayscale slice of mouse brain with neurons highlighted

It’s now or never: Visual events have 100 milliseconds to hit brain target or go unnoticed

Researchers at the National Eye Institute (NEI) have defined a crucial window of time that mice need to key in on visual events.
Rods and cones: Photoreceptors in a human retina

Researchers Find That Nicotinamide May Help Treat Fibrotic Eye Diseases and Mitigate Vision

Nicotinamide, a form of vitamin B3, can inhibit aggressive cell transformations during wound healing and may be key to the development of therapies to treat fibrotic eye diseases that impair vision.
Scientists in the laboratory

Lipid helps heal the eye’s frontline protection

A species of a lipid that naturally helps skin injuries heal appears to also aid repair of common corneal injuries, even when other conditions, like diabetes, make healing difficult, scientists report.
Images of dry AMD retina

NIH researchers discover tooth-enamel protein in eyes with dry AMD

A protein that normally deposits mineralized calcium in tooth enamel may also be responsible for calcium deposits in the back of the eye in people with dry age-related macular degeneration (AMD).
Mouse retinal blood vessels

‘Primitive’ Stem Cells Shown to Regenerate Blood Vessels in The Eye

Researchers turn back the biological hands of time, making adult cells revert to a primitive state with the potential to replace and repair retinal blood vessels.

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