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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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James Golladay and Aman George hold up grant award check

Knights Templar Eye Foundation awards research grant to NEI scientist

National Eye Institute (NEI) Postdoctoral Fellow Aman George, Ph.D., has received a $65,000 grant from the Knights Templar Eye Foundation to identify new drug treatments for vision impairment in children with a type of albinism.
Grantee News

Insight to the Eye Lens

U. Delaware's Salil Lachke identifies new mechanism essential for eye lens development.
Ground squirrel curled up in a nest

NIH researchers develop 'hibernation in a dish' to study how animals adapt to the cold

Researchers at the National Eye Institute have discovered cellular mechanisms that help the 13-lined ground squirrel survive hibernation.

Immune cells in the retina can spontaneously regenerate

Immune cells called microglia can completely repopulate themselves in the retina after being nearly eliminated, according to a new study in mice from scientists at the National Eye Institute (NEI).
Retina organoids mimic the structure and function of the human retina to serve as a platform to study underlying causes of retinal diseases, test new drug therapies, and provide a source of cells for transplantation. credit: David Gamm, M.D., Ph.D., University of Wisconsin-Madison

NIH solicits next-generation retina organoids in prize competition

A competition for radical ideas in the fight against blindness will move to its next phase by challenging participants to build functioning human retina prototypes.
Aqueous humor flows out of the anterior chamber through the open angle where the cornea meets the iris. The open angle consists of two routes: the conventional, trabecular pathway, which includes a spongy layer called the trabecular meshwork, and the non-conventional, uveoscleral pathway, through the ciliary muscle that controls the eye’s focusing mechanism. The majority of fluid flows out via the trabecular pathway, which acts like a one-way valve. About a third of the fluid exits through the uveoscleral p

NEI support paved early pathway for novel glaucoma therapies

The recent approval of two novel medications for glaucoma – the first new medications for the disorder in nearly 18 years – are fruit borne from decades of foundational scientific research supported by the National Eye Institute (NEI).
Computer simulation shows deformation caused by the eye rotating towards the nose

NEI-funded research suggests repetitive strain from eye movement may play a role in glaucoma

Common, unavoidable eye movements may be a cause of glaucoma in people with normal intraocular pressure (normal-tension glaucoma), according to new research supported by the National Eye Institute.
Grantee News

Macular Degeneration: UVA Discovers Trigger That Leads to Vision Loss for Millions

In a major step forward in the battle against macular degeneration, researchers at the University of Virginia School of Medicine have discovered a critical trigger for the damaging inflammation that ultimately robs millions of their sight.
Grantee News

‘Y’ a Protein Unicorn Might Matter in Glaucoma

A protein shaped like a 'Y' made NEI-funded scientists at Georgia Tech do a double-take may change the way they think about the protein which is sometimes implicated in glaucoma.
Eyes with autoimmune uveitis show increased inflammatory cells in the eye (indicated by arrows). Treatment with p35 reduces this inflammatory response. Credit: Charles Egwuagu.

NIH researchers unleash therapeutic potential of IL-35

NIH scientists have simplified manufacturing and dosing of a potential drug candidate for the autoimmune eye disease uveitis—a vision-threatening condition that accounts for about 15 percent of blindness in the U.S.

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