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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Printed cells

NIH researchers use 3D bioprinting to create eye tissue

Scientists used patient stem cells and 3D bioprinting to produce eye tissue that will advance understanding of the mechanisms of blinding diseases.
Two boys smile at camera. The outer portion of the image is darkened, representing vision loss from glaucoma.

New genetic mutation behind childhood glaucoma identified

An international team led by Harvard Medical School scientists has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families.

NEI researchers home in on a new cause of Stargardt disease

Using a new stem-cell based model made from skin cells, scientists found the first direct evidence that Stargardt-related ABCA4 gene mutations affect a layer of cells in the eye called the retinal pigment epithelium (RPE).
Fundus photo showing large white patches

Researchers discover new molecular driver of retinoblastoma

Study from UT Southwestern Medical Center could lead to new treatments for deadly childhood eye cancer.
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Tuncay first to complete NEI international fellowship in ocular genetics

Fulya Yaylacıoğlu Tuncay, M.D., Ph.D., said she gained crucial experience in translational medicine as the first participant in an ocular genetics fellowship program sponsored by NEI and the International Council of Ophthalmology.
Image of an eye with choroideremia, characterized by enlarged RPE cells.

Novel imaging approach reveals important details about rare eye disease choroideremia

Researchers at the National Eye Institute (NEI) have shown for the first time how cells across different tissue layers in the eye are affected in people with choroideremia, a rare genetic disorder that leads to blindness.
Retinal organoid with green photoreceptor outer segments.

NIH researchers develop gene therapy for rare ciliopathy

Researchers from the National Eye Institute (NEI) have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness in early childhood.
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First U.S. patient receives autologous stem cell therapy to treat dry AMD

The patient received the therapy as part of a clinical trial that is the first in the United States to use replacement tissues from patient-derived induced pluripotent stem cells.
Fluorencent microscope image of retinal organoid colored in red, blue and green

Three teams win NIH’s 3D Retinal Organoid Challenge

Three scientific teams that developed physiologically competent retinal organoid systems have won the final phase of the 3D Retinal Organoid Challenge (3D ROC).
Image of retina

High-tech imaging reveals details about rare eye disorder

Using a new imaging technique, researchers from the National Eye Institute have determined that retinal lesions from vitelliform macular dystrophy (VMD) vary by gene mutation.

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