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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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149 items
Image of retina

Scientists successfully test new way to deliver gene therapy​

Researchers at Case Western Reserve University have used a unique method to safely deliver gene therapy to fight a rare, but irreversible, genetic eye disorder known as Stargardt disease.
a scene of two children that is darkened around the edges

New Method Gives Glaucoma Researchers Control Over Eye Pressure

Neuroscientists at the University of South Florida have become the first to definitively prove pressure in the eye is sufficient to cause and explain glaucoma.
Small baby sleeping in hospital.

Tech that detects cause of preemie blindness gets federal nod

An artificial intelligence algorithm that can detect a potentially devastating cause of childhood blindness better than most human experts has been granted breakthrough status by the FDA.
Grantee News

Success of gene therapy for a form of inherited blindness depends on timing

Using a canine model of the vision disorder Leber congenital amaurosis, Penn researchers found that photoreceptor cells continue to deteriorate after treatment if it is given too late.
Diagram of RPE cell loss

Report: Dry AMD requires broad, systems biology approach leveraging big data, multiple disciplines

A large-scale, collaborative, systems biology approach is needed to expedite the discovery of treatments for dry age-related macular degeneration (AMD) – a leading cause of blindness among people 65 and older for which is there is no treatment.
Grantee News

Joslin Researchers Uncover Protective Factor in Diabetic Eye Disease

Researchers at Joslin Diabetes Center have shown that a protein found in the eye can protect against and potentially treat diabetic eye disease.
Microglia in retinal sections of a patient with retinitis pigmentosa

Immune System Can Slow Degenerative Eye Disease, NIH-led Mouse Study Shows

A new study shows that the complement system, part of the innate immune system, plays a protective role to slow retinal degeneration in a mouse model of retinitis pigmentosa, an inherited eye disease.
Grantee News

A step closer to identifying cause of a blinding disease

A recent study, led by researchers at McGill University, offers an important step in unlocking the mystery of Leber hereditary optic neuropathy’s cause.
Grantee News

Experimental Drug Delivers One-Two Punch to Vision Loss

In studies with lab-grown human cells and in mice, Johns Hopkins Medicine researchers have found that an experimental drug may be twice as good at fighting vision loss as previously thought.
Grantee News

With Single Gene Insertion, Blind Mice Regain Sight

Researchers at the University of California, Berkeley, find that restoring opsins with gene therapy can make 'blind' cells light-sensitive; potential human treatment within three years.