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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Fundus photo showing medium drusen

LSU Health New Orleans researchers discover a key failure in AMD that may lead to progression and vision loss

Research suggests that age-related macular degeneration (AMD) decreases an essential fatty acid, preventing the formation of a class of protective molecules and reducing repair potential.
Two boys smile at the camera. Asymmetric dark spots block parts of the image, representing vision loss from diabetic retinopathy.

MSU researchers discover link between cholesterol and diabetic retinopathy

Researchers found that diabetes, age-related health conditions and other metabolic disorders can lead to a buildup of cholesterol in the retina, which could contribute to diabetic retinopathy.

Short-term use of immunosuppressants not linked to cancer risk

Relatively short-term use of immunosuppressant medications to control an inflammatory disease was not associated with an increased risk of later developing cancer, according to new research.
Rhodopsin-bound nanobodies

UC Irvine researchers discover a nanobody which may lead to treatment for retinitis pigmentosa

University of California Irvine (UCI) researchers believe they have discovered a special antibody that may lead to a treatment for an inherited eye disease called retinitis pigmentosa.
Transplanted microglia

Scientists develop new therapeutic model for potentially treating incurable eye diseases

Researchers have successfully transplanted human microglia into mouse retina to create a model for studying eye disease treatments, such as diabetic retinopathy, glaucoma and age-related macular degeneration.

Cell therapy that repairs cornea damage with patient’s own stem cells achieves positive Phase I trial results

Cultivated autologous limbal epithelial cells (CALEC) procedure shown to be safe and feasible with early positive results of restored cornea surfaces or vision gains in four patients with severe chemical burns.

More than meets the eye: New research shows how the visual system contributes to memory

A team of researchers from NYU has demonstrated that the key to understanding working memory relies not only on what one is storing in memory, but also why.

Scientists discover external protein network can help stabilize neural connections

The Noelin family of secreted proteins bind to the external portion of AMPA glutamate receptors and stabilize them on the neuronal cellular membrane, a process necessary for transmission of full-strength signals between neurons.

NEI high school student video contest winners visit NIH

The National Eye Institute (NEI) hosted winners of the 2023 Eye on the Future Video Contest on July 14 on the NIH Campus in Bethesda, Maryland.
Long distance connections in the brain.

Penn Medicine neuroscientists identify brain mechanism that drives focus despite distractions

“Visual-movement” neurons in the front of your brain can help you stay focused in the presence of visual distractions, according to a new study from neuroscientists in the Perelman School of Medicine at the University of Pennsylvania.