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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Nanoparticle. Courtesy of Biorender.

Tiny nanoparticle could have big impact on patients receiving corneal transplants

Using nanoparticles to encapsulate eye medication decreased graft rejection while requiring fewer and smaller doses.

Night vision tests in age-related macular degeneration precisely localize disease mechanisms

Researchers at the University of Alabama at Birmingham discovered that night vision tests at a specific location in the retina will be suitable for assessing treatments and preventions for AMD.

Researchers discover therapeutic target to aid in glaucoma treatment

Indiana University researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma.
Older woman's right eye

New insights: Eye damage in Alzheimer’s disease patients

Cedars-Sinai investigators map changes to the retina that correspond to brain changes in the early stage of Alzheimer's disease, opening a path to earlier diagnosis.
Fundus photograph of age-related macular degeneration showing drusen.

Discovery suggests new way to prevent common causes of vision loss

UVA Health scientists have discovered an unknown contributor to harmful blood vessel growth in the eye that could lead to new treatments for blinding macular degeneration and other common causes of vision loss.
Patient wearing brain pressure measuring device over their eyes.

Low brain pressure could be a risk factor for developing glaucoma

A recent international clinical study demonstrates that low intracranial pressure correlates with impaired patient vision, especially in the nasal zone.

HSC researcher discovered a potential cause for keratoconus

Researchers at the University of North Texas Health Science Center are the first to characterize extracellular vesicles in the tears of patients with keratoconus.
Synapses between neurons in thalamus and cortex.

Sparse, small, but diverse neural connections help make perception reliable, efficient

In a study from the Picower Institute at MIT, the first detailed mapping and modeling of thalamus inputs onto visual cortex neurons show brain leverages “wisdom of the crowd” to process sensory information.
A person with diabetes checks their blood sugar

Researchers unravel why episodes of low blood sugar worsen eye disease in people with diabetes

Researchers at Johns Hopkins Medicine say they have linked transient low blood sugar levels that occur in people with diabetes with a molecular pathway that is turned on in oxygen-starved cells in the eye.
Animation of abnormal blood vessels bleeding into the center of the eye due to proliferative diabetic retinopathy. Photo credit: National Eye Institute. Watch video.

Type 1 diabetes: Maintaining the enzyme ACE2 in the gut prevents diabetic blindness

Study from University of Alabama at Birmingham suggests that a leaky small intestine that weakens the barrier between gut bacteria and the blood system may drive diabetic retinopathy.

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