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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Grantee News

Experimental Drug Delivers One-Two Punch to Vision Loss

In studies with lab-grown human cells and in mice, Johns Hopkins Medicine researchers have found that an experimental drug may be twice as good at fighting vision loss as previously thought.
Greens, beans and dairy products arranged on a table

NIH Study Finds No Evidence That Calcium Increases Risk of AMD

Eating a calcium-rich diet or taking calcium supplements does not appear to increase the risk of age-related macular degeneration (AMD), according to the findings of a study by scientists at the National Eye Institute (NEI).
Grantee News

With Single Gene Insertion, Blind Mice Regain Sight

Researchers at the University of California, Berkeley, find that restoring opsins with gene therapy can make 'blind' cells light-sensitive; potential human treatment within three years.
Two boys smile at camera. Dark spot in center of image represents vision loss from AMD.

NIH Researchers Home in on Genes Linked to Age-Related Macular Degeneration

National Eye Institute scientists led a collaborative study and zeroed in on genes associated with age-related macular degeneration (AMD), a leading cause of vision loss and blindness among people age 65 and older.
Side-by-side panels showing retinal vessels. Left panel filled with green, right panel much less green.

Faulty molecular master switch may contribute to AMD

A signaling pathway controlled by transforming growth factor β (TGF-β) could be involved in the progression of age-related macular degeneration (AMD).
A scanning electron micrograph image shows a polarized RPE monolayer on a biodegradable scaffold. The image is colored to highlight the scaffold in blue, three RPE cells (brown), and the apical processes of cells in RPE monolayer are light green.

NIH researchers rescue photoreceptors, prevent blindness in animal models of retinal degeneration

Using a novel patient-specific stem cell-based therapy, researchers at the National Eye Institute (NEI) prevented blindness in animal models of geographic atrophy, the advanced “dry” form of age-related macular degeneration (AMD)...
Images show multimodal technique using adaptive optics and angiography to simultaneously see photoreceptors (left), retinal pigment epithelial cells (center), and choriocapillaris in the living human eye.

NIH scientists combine technologies to view the retina in unprecedented detail

By combining two imaging modalities—adaptive optics and angiography—investigators at the National Eye Institute (NEI) can see live neurons, epithelial cells, and blood vessels deep in the eye’s light-sensing retina.
Artistic image shows Müller glia-derived rod photoreceptors.

NIH-funded researchers reverse congenital blindness in mice

Researchers funded by the National Eye Institute (NEI) have reversed congenital blindness in mice by changing supportive cells in the retina called Müller glia into rod photoreceptors.
Grantee News

Eye conditions provide new lens for screening for Alzheimer’s

Researchers from the University of Washington find link between certain eye conditions and the risk for Alzheimer's disease.

Immune cells in the retina can spontaneously regenerate

Immune cells called microglia can completely repopulate themselves in the retina after being nearly eliminated, according to a new study in mice from scientists at the National Eye Institute (NEI).

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