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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Fundus photograph of age-related macular degeneration showing drusen.

International Study Reveals New Genetic Clues to Age-Related Macular Degeneration

An international study of about 43,000 people has significantly expanded the number of genetic factors known to play a role in age-related macular degeneration (AMD), a leading cause of vision loss among people age 50 and older.
The findings suggest that people may be able to lower their risk of AMD by eating a healthy diet, exercising and by not smoking.

Diet, Exercise, Smoking Habits and Genes Interact to Affect AMD Risk

People with a genetic predisposition for age-related macular degeneration (AMD) significantly increased their odds of developing the blinding eye disorder if they had a history of smoking and did not exercise or eat enough fruits and vegetables.
NIH study raises doubt about any benefits omega-3 and dietary supplements like these may have for cognitive decline. (Photo courtesy of NEI)

NIH Study Shows no Benefit of Omega-3 or Other Nutritional Supplements for Cognitive Decline

While some research suggests that a diet high in omega-3 fatty acids can protect brain health, a large clinical trial by researchers at the National Institutes of Health found that omega-3 supplements did not slow cognitive decline in older persons.
Grantee News

New clues found to vision loss in macular degeneration​​​

Scientists at Washington University School of Medicine in St. Louis have identified a pathway that leads to the formation of atypical blood vessels that can cause blindness in people with age-related macular degeneration.
Grantee News

Patients with AIDS at Increased Risk of Developing Age-Related Macular Degeneration

Patients with acquired immunodeficiency syndrome (AIDS) have a four-fold increase in their risk of developing intermediate-stage age-related macular degeneration (AMD) compared to people of the same age who are not infected with HIV.
Grantee News

Stem Cell Injection May Soon Reverse Vision Loss Caused By Age-Related Macular Degeneration

An injection of stem cells into the eye may soon slow or reverse the effects of early-stage age-related macular degeneration, according to new research from scientists at Cedars-Sinai.
Grantee News

LSU Health New Orleans Makes Discovery Key to Preventing Blindness and Stroke Devastation

Researchers at the Louisiana State University Neuroscience Center of Excellence have discovered gene interactions that determine whether cells live or die in such conditions as age-related macular degeneration and ischemic stroke.
Degenerated RPE cells from mice with geographic atrophy are shown at left. Treating the mice with NRTIs protected the RPE cells. Photos courtesy of Jayakrishna Ambati, M.D.

HIV drugs show promise for “dry” AMD

A class of medications long used to curb HIV infection shows promise as a therapy for age-related macular degeneration (AMD), suggest findings from an NIH-funded study.
Grantee News

Proteins critical to wound healing identified

Research at Washington University School of Medicine in St. Louis may have implications for treating diseases involving abnormal blood vessel growth, such as the impaired wound healing often seen in diabetes.
An occupational therapist at Thomas Jefferson University works with a patient who has low vision. Credit: Thomas Jefferson University.

Rehabilitation helps prevent depression from age-related vision loss

Depression is a common risk for people who have lost their vision from age-related macular degeneration (AMD), but a new study shows that a type of rehabilitation therapy can cut this risk in half.