51 items

Gene Found that Causes Eyes to Wither in Cavefish

June 2, 2020

University of Maryland-led study identified the first gene responsible for eye loss in cavefish, revealing connection to a human vascular disease.

New gene therapy delivery system aims for precision

May 4, 2020

In a novel approach to gene therapy, scientists funded by the National Eye Institute (NEI) report using gold nanoparticles and light to target specific cells in mouse retina.

NEI researchers link age-related DNA modifications to susceptibility to eye disease

April 21, 2020

National Eye Institute (NEI) researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression.

Scientists successfully test new way to deliver gene therapy​

March 6, 2020

Researchers at Case Western Reserve University have used a unique method to safely deliver gene therapy to fight a rare, but irreversible, genetic eye disorder known as Stargardt disease.

Potential Way to Halt Blinding Macular Degeneration Identified

January 22, 2020

Researchers at the University of Virginia have successfully treated age-related macular degeneration (AMD) in mice after finding an unexpected link between the two main forms of the blinding eye disease.

UNH Researchers Solve Protein Structure Associated with Inherited Retinal Diseases

December 23, 2019

Researchers at the University of New Hampshire have reported the first structural model for a key enzyme, and its activating protein, that can play a role in some genetically inherited eye diseases like retinitis pigmentosa and night blindness.

LSU Health discovers critical role of two proteins in vision and preventing blinding eye diseases

December 10, 2019

LSU researchers have discovered unique patterns of genetic activity that may lead to the development of blinding retinal diseases.

Discovery in monkeys could lead to treatment for blindness causing syndrome

October 25, 2019

Oregon National Primate Research Center at OHSU reports first-ever nonhuman primate model for Bardet-Biedl Syndrome

Nano-sized solution for efficient and versatile CRISPR gene editing

September 17, 2019

CRISPR gene-editing technology holds tremendous promise for treating or curing a wide range of devastating disorders, including vision loss.

NEI Researchers Awarded Grants by the Knights Templar Eye Foundation

July 11, 2019

The Knights Templar Eye Foundation has awarded two NEI scientists grants to research inherited retinal degenerations, diseases that can cause blindness in early childhood.