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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Researchers Discover Clue to How to Protect Neurons and Encourage Their Growth

A multi-university team identified a family of enzymes called GCK-IV kinases whose inhibition is robustly neuroprotective, while also permitting axon regeneration.
Axon nerve fibers on a red background

Vision Revision

Scientists reverse age-related vision loss, glaucoma damage in mice.

LSU Health New Orleans Discovers Drug Development Target for Retinal Dystrophies

A new study shows that deleting one of the inhibitors of the RPE65 gene in a mouse model that carries a human disease mutation prevents degeneration of cone photoreceptors that are used for daytime high-resolution color vision.
diagram of the eye

Unique Schwann Cells: The Eyes Have It

A new study from University of Connecticut details a method of characterizing every cell in the cornea using an approach known as single-cell RNA sequence analysis to answer questions about the cornea’s healing process.
Color-coded map of gene expression. Credit: Desplan Lab/NYU

NYU researchers create a "developmental atlas" of gene expression in neurons

New York University researchers created a “developmental atlas” of gene expression in neurons, using gene sequencing and machine learning to categorize more than 250,000 neurons in the brains of fruit flies.
Samarendra Mohanty and Subrata Batabyal

Scientists use gene therapy and a novel light-sensing protein to restore vision in mice

A newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells using gene therapy.

UCI-led study reveals significant restoration of retinal and visual function following gene therapy

New generation CRISPR technology lays foundation for therapeutics to treat a wide range of inherited ocular diseases

FAU Researchers receive $1.3 million NIH grant for stem cell research

Researchers from Florida Atlantic University’s Schmidt College of Medicine hope to conquer a major limitation in the ability for scientists to engineer tissues for regenerative therapies for age-related and degenerative diseases.
Scientist viewed through a laboratory shelf filled with bottles

AGI-supported researchers discover gene pathways that regenerate neurons between the eye and the brain

A team of researchers has identified networks of genes that allow neurons to regenerate in animals like zebrafish.
Retina flattened to 4 lobes, stained yellow and blue

LSU Health show nonharmful stress protects against disease in offspring

Researchers funded by the National Eye Institute show in a mammalian model the reprogramming of heritability to promote disease resilience in the next generation.