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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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135 items
David Gamm in the laboratory

UW researchers devise approach to treat rare, incurable form of blindness

Scientists at the University of Wisconsin‒Madison have published a proof-of-concept method to correct an inherited form of macular degeneration that causes blindness, and that is currently untreatable.
neurons

Neurons are genetically programmed to have long lives

Researchers reveal a mechanism by which long-term survival of neurons is intrinsically programmed during development.
Computerized image of an eyeball, optic nerve and brain.

Study points to potential new approach to treating neurodegenerative diseases like glaucoma and Alzheimer’s disease

Researchers have shown for the first time that when one optic nerve in the eye is damaged, as in glaucoma, the opposite optic nerve comes to the rescue by sharing its metabolic energy.
Multicolor image of retina in cross-section

Scientists Use Nanoparticle-Delivered Gene Therapy to Inhibit Blinding Eye Disease in Rodents

In experiments in rats and mice, two Johns Hopkins scientists report the successful use of nanoparticles to deliver gene therapy for blinding eye disease.
Photo with only the center visible

UB-UAB collaboration stimulates rethinking of a degenerative eye disease

Researchers from the University of Buffalo have found new information about retinitis pigmentosa, a condition that begins in childhood with night blindness and loss of peripheral vision.
Close up of woman's face.

Seeing corneal degeneration in a new light

The molecular changes that lead to Fuchs’ endothelial corneal dystrophy (FECD) occur decades before the disease causes blurry vision and other noticeable symptoms in patients, new research by UT Southwestern scientists shows.
Microscopy image of lens and zone fibers stained red, blue and green.

New research on Marfan syndrome focuses on eyes

New NEI-supported research provides insight into the eye conditions associated with Marfan syndrome, where weakened zonule fibers cause vision problems.
Image of fluorescent cells in iris-like pattern

IU researchers model human stem cells to identify degeneration in glaucoma

Using human stem cell models, researchers at Indiana University School of Medicine found they could analyze deficits within cells damaged by glaucoma, with the potential to use this information to develop new strategies to slow the disease process.
Man getting his eyes examined by a doctor using a slit lamp

Retinitis pigmentosa research probes role of the enzyme DHDDS in this genetic disease

Researchers who made a knock-in mouse-model of the genetic disorder retinitis pigmentosa 59, or RP59, found no retinal degeneration or thinning, calling into question the commonly accepted mechanism for RP59.
Surface-dwelling fish with an eye, and pale cave fish without eye

Gene Found that Causes Eyes to Wither in Cavefish

University of Maryland-led study identified the first gene responsible for eye loss in cavefish, revealing connection to a human vascular disease.

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