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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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National Eye Institute

Systemic therapy outperforms intraocular implant for treating uveitis

Systemic therapy consisting of corticosteroids and immunosuppressants preserved vision of uveitis patients better – and had fewer adverse outcomes – than a long-lasting corticosteroid intraocular implant, according to a clinical trial funded by NEI.

NIH-Funded Scientists Home in on Molecular Causes of Secondary Cataract

Four to 12 percent of people undergoing cataract surgery to replace a cloudy lens with a clear artificial one develop posterior capsule opacification (PCO).
Xu Wang with Wai Wong in lab

Breast cancer drug dampens immune response, protecting light-sensing cells of the eye

The breast cancer drug tamoxifen appears to protect light-sensitive cells in the eye from degeneration, according to a new study in mice.
Grantee News

Pain medicine helps preserve vision in model of inherited retinal degeneration

A pain medicine that potently activates a receptor vital to a healthy retina appears to help preserve vision in an animal model of severe retinal degeneration, NEI-funded scientists at Medical College of Georgia at Augusta University report.
Grantee News

Scientists reveal new target for anti-lymphangiogenesis drugs

A new study funded in part by NEI and published in Nature Communications reveals a mechanism involved in the regulation of a process called lymphangiogenesis, specifically in corneal transplants and infectious eye disease.
Grantee News

The Brain’s Gardeners: Immune Cells ‘Prune’ Connections Between Neurons

A new study by at the University of Rochester shows that cells normally associated with protecting the brain from infection and injury also play an important role in rewiring the connections between nerve cells.
Dr. Rachel Bishop and Dr. Allen Eghrari, from the Johns Hopkins University Wilmer Eye Institute, shown here with the advanced imaging technologies being used for the PREVAIL III study in Monrovia, Liberia.

NEI Team in Liberia Investigates Ocular Effects Among Ebola Survivors

Following the 2014 Ebola outbreak in West Africa that took the lives of more than 11,200 people in the region, the National Eye Institute, part of the National Institutes of Health, has deployed a team of clinicians and technical experts to Monrovia...
Schematic of microbiota interacting with ocular immune system.

In Uveitis, Bacteria in Gut May Instruct Immune Cells to Attack the Eye

The inflammatory eye disorder autoimmune uveitis occurs when a person’s immune system goes awry, attacking proteins in the eye.
Grantee News

New clues found to vision loss in macular degeneration​​​

Scientists at Washington University School of Medicine in St. Louis have identified a pathway that leads to the formation of atypical blood vessels that can cause blindness in people with age-related macular degeneration.
Children who slept near a cooking fire were four times as likely to develop severe trachoma compared with children who slept in ventilated rooms without cooking fires. This child’s severe trachoma led to loss of vision in his left eye. Photo courtesy of Raul Vasquez/Orbis.

Trachoma Risk Tied to Sleeping Near Cooking Fires, Lack of Ventilation

Children who sleep in unventilated rooms with cooking fires are at greater risk for severe trachoma, a leading cause of preventable blindness in developing countries.

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