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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Photo shows microscopy image of exosomes in green surrounding rentinal ganglion cells in yellow and orange.

Stem cell secretions may protect against glaucoma

A new study in rats shows that stem cell secretions, called exosomes, appear to protect cells in the retina, the light-sensitive tissue in the back of the eye.
James W. Gollady, Jr., Right Eminent Department Commander (right), presents Hotaling with a check from the Knights Templar Eye Foundation. “I think this award is extremely important to pave a pathway for me in medical research,” said Hotaling. (Joe Balintfy, NEI)

NEI Scientist Receives Research Grant from Knights Templar Eye Foundation

NEI research fellow Nathan Hotaling, PhD, has been awarded a $65,000 grant from the Knights Templar Eye Foundation to develop a stem cell-based system to study Best disease, a genetic disorder that can cause progressive vision loss.
Grantee News

CRISPR Used to Repair Blindness-causing Genetic Defect in Patient-derived Stem Cells

Columbia University Medical Center (CUMC) and University of Iowa scientists have used a new gene-editing technology called CRISPR to repair a genetic mutation responsible for retinitis pigmentosa (RP), an inherited condition.
Grantee News

Researchers Grow Retinal Nerve Cells in the Lab

Johns Hopkins researchers have developed a method to efficiently turn human stem cells into retinal ganglion cells, the type of nerve cells located within the retina that transmit visual signals from the eye to the brain.
Grantee News

Stem Cell Injection May Soon Reverse Vision Loss Caused By Age-Related Macular Degeneration

An injection of stem cells into the eye may soon slow or reverse the effects of early-stage age-related macular degeneration, according to new research from scientists at Cedars-Sinai.
Grantee News

​Stem Cells from Wisdom Teeth Can Be Transformed into Corneal Cells

Stem cells from the dental pulp of wisdom teeth can be coaxed to turn into cells of the eye’s cornea and could one day be used to repair corneal scarring due to infection or injury.
Retinal pigment epithelium derived from induced pluripotent stem cells. Photo credit: Dr. Kapil Bharti.

Gene profiling technique to accelerate stem cell therapies for eye diseases

Researchers at the National Institutes of Health have developed a technique that will speed up the production of stem-cell derived tissues.
Grantee News

Patient-Specific Stem Cells and Personalized Gene Therapy

Columbia University Medical Center (CUMC) researchers have created a way to develop personalized gene therapies for patients with retinitis pigmentosa (RP), a leading cause of vision loss.
Grantee News

Researchers Use Human Stem Cells to Create Light-Sensitive Retina in a Dish

Using a type of human stem cell, researchers have created a three-dimensional complement of human retinal tissue in the laboratory, which notably includes functioning photoreceptor cells capable of responding to light
National Eye Institute logo.

Stem Cell Procedure Protects Mice from Degenerative Retinal Diseases; May Be Promising for People with Similar Retinal Diseases

An experimental 'rescue' of retinas by treating eyes with certain stem cells has been shown to preserve visual function in mice that were genetically predisposed to degenerative diseases of the retina.

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