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Retinitis Pigmentosa Clear all filters

59 items

Before Retinal Cells Die, They Regenerate, Penn Vet Blindness Study Finds

March 18, 2016

Researchers at the University of Pennsylvania showed that in a form of canine blindness retinal cells continue to differentiate for a period of time early in a dog’s life before overwhelming cell death caused the retina to degenerate.

CRISPR Used to Repair Blindness-causing Genetic Defect in Patient-derived Stem Cells

January 27, 2016

Columbia University Medical Center (CUMC) and University of Iowa scientists have used a new gene-editing technology called CRISPR to repair a genetic mutation responsible for retinitis pigmentosa (RP), an inherited condition.

The researchers developed a technique to study live cells in patches of retina, shown here by confocal microscopy. After 2 hours, the vast majority of the cells are alive (green); only a few cells at the perimeter have died (stained red with a dye).

Retinal Cells Work with Little Reserve Energy; May Explain Vulnerability to Eye Diseases

January 8, 2016

Our eyes are especially demanding when it comes to energy: Along with our brain, they require a substantial amount of power to keep them functioning and healthy.

Gene Editing Technique Improves Vision in Rats with Inherited Blindness

January 7, 2016

A new technique that has the potential to treat inherited diseases by removing genetic defects has been shown for the first time to hinder retinitis pigmentosa, a degenerative eye disease with no known cure that can lead to blindness.

USC Eye Institute researchers discover a way to improve image sharpness for blind people with retinal implants

December 17, 2015

Retinal implants that deliver longer pulses of electrical current may noticeably improve image sharpness for individuals who have lost their sight due to retinitis pigmentosa, according to a new study.

Image of gene therapy preserved vision in a study involving dogs.

Gene Therapy Staves Off Blindness from Retinitis Pigmentosa in Canine Model

October 13, 2015

Gene therapy preserved vision in a study involving dogs with naturally occurring, late-stage retinitis pigmentosa, according to research funded by the National Eye Institute (NEI), part of the National Institutes of Health.

A microglial cell (green) extends spider-like arms to capture and consume rod photoreceptor cells (blue). Credit: Dr. Wai Wong, NEI.

In Blinding Eye Disease, Trash-Collecting Cells go Awry, Accelerate Damage

July 2, 2015

Spider-like cells inside the brain, spinal cord and eye hunt for invaders, capturing and then devouring them. These cells, called microglia, often play a beneficial role by helping to clear trash and protect the central nervous system against infection.

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