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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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NEI researchers discover cellular events that precede neurodegenerative eye disease

Molecular and cellular changes in rod photoreceptors are detectable in a mouse model of retinal degeneration several days prior to observable morphological changes, according to researchers at the National Eye Institute.
Stained image of retina

Correcting night blindness in dogs

University of Pennsylvania researchers have developed a gene therapy that restores dim-light vision in dogs with a congenital form of night blindness, offering hope for treating a similar condition in people.
Green retinal ganglion cell spreads dendrites in all directions.

Antabuse may help revive vision in people with progressive blinding disorders

Researchers at the University of California, Berkeley, have found that a drug once widely used to wean alcoholics off of drinking helps to improve sight in mice with retinal degeneration.
mouse retina

UCI researchers discover cause, develop pharmacological treatment for reducing retinitis pigmentosa vision loss

Inhibiting ceramide accumulation in the retina helps preserve the retina’s structure and function, and improves vision.
Rod outer segment showing connector

UC Irvine researchers reveal molecular mechanisms of eye disease using cryo-electron tomography

Understanding the key structural determinants of a highly specialized membrane in the eye could lead to new treatments.
Mother and her daughter smile for the camera

Genomic Study Revealing Among Diverse Populations with Inherited Retinal Disease

International effort identified new and different causative gene variants for a group of diseases that can lead to severe vision loss or blindness.

Gene therapy shows promise in treating rare eye disease in mice

A gene therapy protects eye cells in mice with a rare disorder that causes vision loss, especially when used in combination with other gene therapies, shows a study published in eLife.
photoreceptors and retinal ganglion cells are shown on a video playbutton.

An artificial retina engineered from ancient protein heads to space

LambdaVision, the Farmington, Connecticut-based biotech firm that developed the artificial retina, is exploring optimizing production of an artificial retina in space, in a series of missions to the International Space Station.
City scene at night. Credit: Luca Bravo on Unsplash

How is night vision maintained during retinal disease?

New research from the University of Utah provides insight on how people with retinal degenerative disease can maintain their night vision for a relatively long period of time.
Photo with only the center visible

UB-UAB collaboration stimulates rethinking of a degenerative eye disease

Researchers from the University of Buffalo have found new information about retinitis pigmentosa, a condition that begins in childhood with night blindness and loss of peripheral vision.