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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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59 items
Man getting his eyes examined by a doctor using a slit lamp

Retinitis pigmentosa research probes role of the enzyme DHDDS in this genetic disease

Researchers who made a knock-in mouse-model of the genetic disorder retinitis pigmentosa 59, or RP59, found no retinal degeneration or thinning, calling into question the commonly accepted mechanism for RP59.
photoreceptors

Researchers restore sight in mice by turning skin cells into light-sensing eye cells

Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision. The lab-made rods enabled blind mice to detect light after the cells were transplanted into the animals’ eyes.
Eye chart for testing vision

Therapy could improve, prolong sight in those suffering vision loss

Millions of Americans are progressively losing their sight as cells in their eyes deteriorate, but a new therapy developed by researchers at the University of California, Berkeley, could help prolong useful vision and delay total blindness.
Model of protein structure with 4 protein chains

UNH Researchers Solve Protein Structure Associated with Inherited Retinal Diseases

Researchers at the University of New Hampshire have reported the first structural model for a key enzyme, and its activating protein, that can play a role in some genetically inherited eye diseases like retinitis pigmentosa and night blindness.
Rhesus macaque monkey

Discovery in monkeys could lead to treatment for blindness causing syndrome

Oregon National Primate Research Center at OHSU reports first-ever nonhuman primate model for Bardet-Biedl Syndrome
Grantee News

Disruption of glucose transport to rods and cones shown to cause vision loss in retinitis pigmentosa

Retinitis pigmentosa (RP) is a common hereditary eye disorder that leads to the gradual deterioration of rod cells causing reduced peripheral vision and night vision. Subsequent loss of cone photoreceptors cause the loss of high-resolution daylight...
7 men look at the camera in a group portrait

NEI Researchers Awarded Grants by the Knights Templar Eye Foundation

The Knights Templar Eye Foundation has awarded two NEI scientists grants to research inherited retinal degenerations, diseases that can cause blindness in early childhood.
Microglia in retinal sections of a patient with retinitis pigmentosa

Immune System Can Slow Degenerative Eye Disease, NIH-led Mouse Study Shows

A new study shows that the complement system, part of the innate immune system, plays a protective role to slow retinal degeneration in a mouse model of retinitis pigmentosa, an inherited eye disease.
Grantee News

With Single Gene Insertion, Blind Mice Regain Sight

Researchers at the University of California, Berkeley, find that restoring opsins with gene therapy can make 'blind' cells light-sensitive; potential human treatment within three years.
Grantee News

Therapy Could Improve, Prolong Sight in Those Suffering Vision Loss

A new therapy developed by researchers at the University of California, Berkeley, could help prolong useful vision and delay total blindness for people with retinitis pigmentosa.

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