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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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107 items
Images of a patient eye with new TIMP3 maculopathy

NIH researchers discover new genetic eye disease

June 8, 2022

Researchers from the National Eye Institute (NEI) have identified a new disease that affects the macula, a small part of the light-sensing retina needed for sharp, central vision.

Noninvasive technique collects sufficient tear fluid to look for biomarkers of health and disease

May 27, 2022

Scientists from Augusta University have fine-tuned a non-invasive and efficient way to evaluate the tear film for clues about wellness and disease.
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Retinal cell map could advance precise therapies for blinding diseases

May 6, 2022

Researchers have identified distinct differences among the cells comprising a tissue in the retina that is vital to human visual perception. The scientists from the National Eye Institute (NEI) discovered five subpopulations of retinal pigment epithelium.
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How do our eyes stay focused on what we reach for? Researchers uncover how our gaze is “anchored” in the brain

April 20, 2022

Findings offer new insights into how our movements are coordinated
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Ultrasound gave us our first baby pictures. Can it also help the blind see?

April 13, 2022

The research team in the USC Viterbi School of Engineering’s Department of Biomedical Engineering is exploring a non-surgical solution that could restore sight by using another of the five senses. Sound.

New UCI-led study lays foundation for establishing base editing as a one-time, durable treatment for inherited retinal degeneration

April 5, 2022

A new study indicates base editing may provide long-lasting retinal protection and prevent vision deterioration in patients with inherited retinal degeneration, specifically in Leber congenital amaurosis (LCA) patients.
Photoreceptor degeneration tied to lipofuscin accumulation.

Advancing a treatment for a common eye disease that lacks one

April 1, 2022

The road from discovering a potential drug to getting the therapy into the hands of patients is a long and uncertain one. An NIH program called Blueprint Neurotherapeutics Network helps basic researchers prep for clinical trials and regulatory approval.
Stained image of retina

Correcting night blindness in dogs

March 22, 2022

University of Pennsylvania researchers have developed a gene therapy that restores dim-light vision in dogs with a congenital form of night blindness, offering hope for treating a similar condition in people.
Green retinal ganglion cell spreads dendrites in all directions.

Antabuse may help revive vision in people with progressive blinding disorders

March 18, 2022

Researchers at the University of California, Berkeley, have found that a drug once widely used to wean alcoholics off of drinking helps to improve sight in mice with retinal degeneration.
retina blood vessels

Indiana University-led study shows human induced pluripotent stem cells improve visual acuity, vascular health

March 17, 2022

Researchers improved vision in a type 2 diabetes mouse model by reprogramming blood cells into endothelial cells with vessel reparative properties similar to endothelial colony forming cells.