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Retinal pigment epithelial cells stained green and magenta

CU Researchers Provide First Evidence Linking Extracellular Vesicles with Drusen Formation and Age-Related Macular Degeneration

November 12, 2021

CellSight researchers at the University of Colorado School of Medicine are offering the first evidence connecting drusen formation, or yellowish deposits that accumulate under the retina, with extracellular vesicles and age-related macular degeneration.

Retinoid Therapy May Improve Vision in People with Rare Genetic Disorder, According to Study in Mice

November 9, 2021

Researchers have uncovered the mechanism of vision loss in Usher syndrome, yielding additional drug targets for eventual development of better therapies.

Small amounts of carbon monoxide may help protect vision in diabetes

November 4, 2021

The Medical College of Georgia scientists have early evidence that HBI-002, a low-dose oral compound, can safely reduce oxidative stress and inflammation in the retina, both early, major contributors to diabetic retinopathy.
Brad Gelfand, Ph.D., in the laboratory

Prozac Pegged as Potential Treatment for a Leading Cause of Blindness

October 21, 2021

An antidepressant best known as Prozac could offer the first treatment for the leading cause of blindness among people over 50, new research from the University of Virginia School of Medicine suggests.
A diagram of the eye with a green arrow showing how fluid normally passes through the space between the iris and the cornea and drains out of the eye back into the bloodstream.

A new treatment for glaucoma?

October 18, 2021

A Northwestern Medicine study in mice has identified new treatment targets for glaucoma, including preventing a severe pediatric form of glaucoma, as well as uncovering a possible new class of therapy for the most common form of glaucoma in adults.

Toxic DNA Buildup May Drive Macular Degeneration

September 30, 2021

Damaging DNA builds up in the eyes of patients with geographic atrophy, an untreatable, poorly understood form of age-related macular degeneration that causes blindness, new research from the University of Virginia School of Medicine reveals.

Novel approach reverses amblyopia in animals

September 1, 2021

By temporarily suspending retinal activity in the non-amblyopic eye of animal models, neuroscientists restrengthened the visual response in the amblyopic eye, even at ages after the critical period when patch therapy fails.

University of Oregon researchers develop gene therapy for eye disease

August 3, 2021

Researchers have developed a new gene therapy that could eventually provide an alternative treatment for Fuchs’ endothelial corneal dystrophy, a genetic eye disease affecting roughly one in 2,000 people globally.
Neurons (green) and their supporting astrocytes (red), created in a petri dish from stem cells.

Cell-replacement Therapies for Visual System Disorders

July 30, 2021

Two translational studies at the Vanderbilt Eye Institute are targeting photoreceptors and retinal ganglion cells (RGCs) to restore vision through regeneration of the retina. The research is funded by the NEI Audacious Goals Initiative.
OCT image of a retina

New biomarkers may detect early eye changes that can lead to diabetes-related blindness

July 26, 2021

New biomarkers found in the eyes could unlock the key to helping manage diabetic retinopathy, and perhaps even diabetes, according to new research conducted at the Indiana University School of Optometry.