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498 items
OCT image of a retina

New biomarkers may detect early eye changes that can lead to diabetes-related blindness

July 28, 2021

New biomarkers found in the eyes could unlock the key to helping manage diabetic retinopathy, and perhaps even diabetes, according to new research conducted at the Indiana University School of Optometry.
Two hat-shaped objects, one pointing towards the viewer (concave) and one away from the viewer (convex)

Scientists uncover how decisions about what we see are relayed back through the brain

July 27, 2021

Researchers at the National Institutes of Health have discovered that decisions based on visual information is broadcast widely to neurons in the visual system, including to those that are not being used to make the decision.
Female shown from overhead standing with her eye open receiving OCT scan.

NEI-funded technology promises to broaden access to retinal scanning

July 22, 2021

A National Eye Institute-funded project at Duke University has yielded a fully automated optical coherence tomography (OCT) device that does not require a trained operator and promises to broaden access to retinal imaging technology.
Eye is shown connected to visual processing regions of the brain via the optic nerve. Enlargement of retina shows photorecetors, biopolar cells and retinal ganglion cells.

Scientists discover gene therapy provides neuroprotection to prevent glaucoma vision loss

July 22, 2021

A form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma, according to research supported by NIH’s National Eye Institute. The findings suggest a way forward for developing neuroprotective therapies for glaucoma.
Two boys smile at camera. Dark spot in center of image represents vision loss from AMD.

HtrA1 augmentation is potential therapy for age-related macular degeneration

July 19, 2021

Research from the University of Utah explains why people with genetic variants may develop age-related macular degeneration (AMD) and identifies a potential therapeutic pathway for slowing disease progression.
Tiarnan Keenan

Patients use device to monitor AMD at home

July 16, 2021

Tiarnan Keenan, NEI Division of Epidemiology and Clinical Applications, and colleagues found that people with age-related macular degeneration (AMD) can successfully use the Notal Home OCT device to monitor their disease.
eye anatomy graphic

Melanoma of the eye: preclinical tests show path toward treatment

July 14, 2021

Researchers at UAB have discovered a small molecule inhibitor that dampens the potent drivers of uveal melanoma.
neurons

How neurons get past "no"

June 24, 2021

When looking at a complex landscape, the eye needs to focus in on important details without losing the big picture. Now, a new study by Salk scientists shows how inhibitory neurons play a critical role in this process.z
Brain illustration with recycling logo

NIH-funded study shows children recycle brain regions when acquiring new skills

June 17, 2021

Scientists studied the brain activity of school-aged children during development and found that regions that activated upon seeing limbs (hands, legs, etc.) subsequently activated upon seeing faces or words when the children grew older.
Cells with red nuclei and long green processes

Scientists unravel the function of a sight-saving growth factor

June 16, 2021

Researchers at the National Eye Institute (NEI) have determined how certain short protein fragments, called peptides, can protect neuronal cells found in the light-sensing retina layer at the back of the eye.