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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Photoreceptor precursors

Progress toward a stem cell–based therapy for blindness

July 28, 2022

A multi-institutional effort led by researchers at the UPenn School of Veterinary Medicine is taking steps to develop an effective technique to regenerate photoreceptors cells and restore sight in people with vision disorders.
Image of retina

High-tech imaging reveals details about rare eye disorder

July 28, 2022

Using a new imaging technique, researchers from the National Eye Institute have determined that retinal lesions from vitelliform macular dystrophy (VMD) vary by gene mutation.
Graph showing that odd ratio for advanced vision loss for African Americans is significantly higher than for non-hispanic whites.

Black patients found six times more likely to have advanced vision loss after glaucoma diagnosis than white patients

July 25, 2022

Black patients have a dramatically higher risk of advanced vision loss after a new diagnosis of primary open angle glaucoma (POAG) when compared to white patients, according to a new study from New York Eye and Ear Infirmary of Mount Sinai (NYEE).

Employee Offers Personal Account of NIH-Supported Clinical Research

July 22, 2022

Dr. David Kosub shares a first-hand experience of participating in the National Ophthalmic Disease Genotyping and Phenotyping Network (eyeGENE).

NIH study finds loss of ‘youth’ protein may drive aging in the eye

July 18, 2022

Loss of the protein pigment epithelium-derived factor (PEDF), which protects retinal support cells, may drive age-related changes in the retina, according to a new study in mice from the National Eye Institute.
Chirag Jhaveri, MD, examines the eyes of a patient.

A type of ‘step therapy’ is an effective strategy for diabetic eye disease

July 14, 2022

Clinical trial results from the DRCR Retina Network suggest that a specific step strategy gives results similar to starting off with the higher-priced drug.
ABC cells in culture

LSU Health New Orleans Develops New Human Cell Line to Study Blinding Eye Disorders

July 12, 2022

Scientists at LSU Health New Orleans Neuroscience Center of Excellence have developed a new, experimental human cell line from retinal pigment epithelial cells.
Functional map of inhibitory neurons in visual cortex

Experience Required: A role for vision in the development of inhibitory networks

July 12, 2022

New research from the Max Planck Florida Institute for Neuroscience demonstrates that inhibitory and excitatory neuronal circuits of the visual system develop through different processes, even if the organization of the mature circuit is similar.
Joseph Schumacher and David Fitzpatrick

Spot the difference: Brain changes that enable fine visual discrimination learning

July 8, 2022

In a new research study from the Max Planck Florida Institute for Neuroscience, scientists have now discovered the neuronal changes that occur during learning to improve discrimination of closely related visual images.
Vision and non-vision functions use different neuronal circuits in the retina.

NIH researchers decode retinal circuits for circadian rhythm, pupillary light response

July 6, 2022

The eye’s light-sensing retina taps different circuits depending on whether it is generating image-forming vision or carrying out a non-vision function such as regulating pupil size or sleep/wake cycles, according to a new mouse study.

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