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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Micro-molded ‘ice cube tray’ scaffold is next step in returning sight to injured retinas

Researchers at the University of Wisconsin have developed a micro-molded scaffolding photoreceptor “patch” designed to be implanted under a damaged or diseased retina.

University of Maryland School of Medicine study identifies new mechanism that may cause blindness in older adults

Using laboratory-grown roundworms as well as human and mouse eye tissue, researchers have identified a new potential mechanism for age-related macular degeneration—the leading cause of blindness among older adults.
Retina model shows RPE cells, choroidal neovascularization-like pathology, vascular layer, PEG layer, Bruch's membrane, drusen

First-ever lab model of human eye offers hope for macular degeneration patients

NEI-funded research at the University of Rochester has led to the development of a 3D lab model that mimics the part of the human retina affected in age-related macular degeneration.
Anti-VEGF treatment has greatly improved the prognosis for patients with AMD.

National Eye Institute launches data portal for macular degeneration research

The National Eye Institute (NEI) Data Commons now enables researchers to access data from patients with macular degeneration who participated in the Age-related Eye Disease Study 2 (AREDS2).
Rod and cone photoreceptors are shown in greyscale images.

NIH-led team sets new bar in retinal imaging

A team led by scientists at the National Eye Institute (NEI) has noninvasively visualized the light-sensing cells in the back of the eye, known as photoreceptors, in greater detail than ever before.

Research points to new hope for treatment-resistant AMD

The latest research from the John A. Moran Eye Center reveals how an oxidized form of cholesterol can change choroidal endothelial cells into cells that become scars and may wreak havoc in the eyes of age-related macular degeneration (AMD) patients.

New therapeutic approach may help treat age-related macular degeneration effectively

Scientists have found that RUNX1 inhibition presents a new therapeutic approach in the treatment of age-related macular degeneration (AMD), which is the leading cause of blindness in the elderly worldwide.

Breakthrough by Moran Eye Center Scientist, Colleagues Fuels New Line of Disease Research

Scientists at the University of Utah have invented a method for synthesizing large enough quantities of very-long-chain polyunsaturated fatty acids (VLC-PUFAs) to evaluate their potential sight-preserving properties.

HIV Drugs May Help Prevent Blinding Macular Degeneration

Scientists have identified a group of drugs that may help stop a leading cause of vision loss after making an unexpected discovery that overturns a fundamental belief about DNA.
sugar

Study suggests sugary diet endangers waste-eating protein crucial to cellular repair

A protein that functions like the vintage video game Pac-Man, eating toxic cellular waste caused by high sugar intake, is itself compromised by a sugary diet, according to the results of a study in mice with potential implications for humans.