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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Researchers Discover Clue to How to Protect Neurons and Encourage Their Growth

A multi-university team identified a family of enzymes called GCK-IV kinases whose inhibition is robustly neuroprotective, while also permitting axon regeneration.
Axon nerve fibers on a red background

Vision Revision

Scientists reverse age-related vision loss, glaucoma damage in mice.

Discovery Of New Cell May Be Key To Treating Incurable Neurological Diseases

Researchers at Ohio State and the University of Michigan discovered a new type of immune cell that not only rescues damaged nerve cells from death, but partially reverses nerve fiber damage.
Samarendra Mohanty and Subrata Batabyal

Scientists use gene therapy and a novel light-sensing protein to restore vision in mice

A newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells using gene therapy.

UCI-led study reveals significant restoration of retinal and visual function following gene therapy

New generation CRISPR technology lays foundation for therapeutics to treat a wide range of inherited ocular diseases

FAU Researchers receive $1.3 million NIH grant for stem cell research

Researchers from Florida Atlantic University’s Schmidt College of Medicine hope to conquer a major limitation in the ability for scientists to engineer tissues for regenerative therapies for age-related and degenerative diseases.
NEI Audacious Goals Initiative for regenerative medicine in vision identity mark

Eye institute’s audacious quest: What once was lost might now be regrown

The National Eye Institute (NEI) Audacious Goals Initiative (AGI) is exploring the possibility that the natural world holds the keys to restorative therapies that might unlock regenerative powers in humans.
Scientist viewed through a laboratory shelf filled with bottles

AGI-supported researchers discover gene pathways that regenerate neurons between the eye and the brain

A team of researchers has identified networks of genes that allow neurons to regenerate in animals like zebrafish.
Zebrafish

Could a tiny fish hold the key to curing blindness?

NEI-funded scientists are hacking the zebrafish’s innate regenerative capacity to learn how to treat human disease.
City scene at night. Credit: Luca Bravo on Unsplash

How is night vision maintained during retinal disease?

New research from the University of Utah provides insight on how people with retinal degenerative disease can maintain their night vision for a relatively long period of time.