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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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178 items
Photoreceptor precursors

Progress toward a stem cell–based therapy for blindness

julio 28, 2022

A multi-institutional effort led by researchers at the UPenn School of Veterinary Medicine is taking steps to develop an effective technique to regenerate photoreceptors cells and restore sight in people with vision disorders.
Image of retina

High-tech imaging reveals details about rare eye disorder

julio 28, 2022

Using a new imaging technique, researchers from the National Eye Institute have determined that retinal lesions from vitelliform macular dystrophy (VMD) vary by gene mutation.

NIH study finds loss of ‘youth’ protein may drive aging in the eye

julio 18, 2022

Loss of the protein pigment epithelium-derived factor (PEDF), which protects retinal support cells, may drive age-related changes in the retina, according to a new study in mice from the National Eye Institute.
ABC cells in culture

LSU Health New Orleans Develops New Human Cell Line to Study Blinding Eye Disorders

julio 12, 2022

Scientists at LSU Health New Orleans Neuroscience Center of Excellence have developed a new, experimental human cell line from retinal pigment epithelial cells.
Vision and non-vision functions use different neuronal circuits in the retina.

NIH researchers decode retinal circuits for circadian rhythm, pupillary light response

julio 6, 2022

The eye’s light-sensing retina taps different circuits depending on whether it is generating image-forming vision or carrying out a non-vision function such as regulating pupil size or sleep/wake cycles, according to a new mouse study.
NEI scientists Mitra Farnoodian Tedrick and Kapil Bharti with KTEF Commanders

Knights Templar Eye Foundation funds NEI scientist’s search for therapies to treat blinding eye disease

julio 5, 2022

NEI researcher Mitra Farnoodian Tedrick, Ph.D., received a $65,000 grant from the Knights Templar Eye Foundation (KTEF) to identify drugs to treat a rare blinding condition called Stargardt disease.
NEI AGI audacious Goals Initiative for Regenerative Medicine

NEI's regenerative medicine initiative making progress toward its audacious goal

julio 5, 2022

A new report outlines progress toward the National Eye Institute's Audacious Goals Initiative (AGI), an effort to restore vision through research in regenerative medicine. The report, published in Nature Medicine.
Multicolored image of photoreceptors and their long connecting processes, called axons, within a stem cell-derived retinal organoid

U. Wisconsin eye research uncovers how stem cell photoreceptors reach their targets

junio 15, 2022

A new study reveals how photoreceptors grown from stem cells might extend biological wires, known as axons, to contact existing neurons.
Images of a patient eye with new TIMP3 maculopathy

NIH researchers discover new genetic eye disease

junio 8, 2022

Researchers from the National Eye Institute (NEI) have identified a new disease that affects the macula, a small part of the light-sensing retina needed for sharp, central vision.
Comparison of two retinal images.

Gene therapy for rare eye disease safe but lacks efficacy in early trial

mayo 31, 2022

A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, with even the highest dose.