Adie’s pupil is thought to be associated with disease or injury to the ciliary ganglion (a branch of the third cranial nerve). The ciliary ganglion, which lies behind the eye, controls the constriction of the iris muscle. Since the iris cannot constrict normally, persons with Adie’s pupil often experience painful sensitivity to light and blurring of close vision. Since a pupil that responds abnormally to light can also be caused by systemic diseases, compression and other injuries to other parts of the third cranial nerve, medical tests may be done to rule these out. In most cases, the reason for the abnormally reacting pupil of Adie’s syndrome is never found, despite medical efforts to find the cause. The symptoms usually disappear spontaneously, although it may take a year or more.
For information from other health sites, please visit the following webpages:
American Academy of Ophthalmology, Adie tonic pupil
EyeWiki, Adie’s Tonic Pupil
National Organization of Rare Disorders, Adie Syndrome
National Institute of Neurological Disorders and Stroke, Holmes-Adie syndrome Information Page