Publications

Original Papers

See Article Depository

  • Bromberg-Martin ES, Matsumoto M, Nakahara H, Hikosaka O (2010d) Multiple timescales of memory in lateral habenula and dopamine neurons. Neuron 67:499-510.
  • Bromberg-Martin ES, Matsumoto M, Hikosaka O (2010b) Distinct tonic and phasic anticipatory activity in lateral habenula and dopamine neurons. Neuron 67:144-155.
  • Bromberg-Martin ES, Matsumoto M, Hong S, Hikosaka O (2010c) A pallidus-habenula-dopamine pathway signals inferred stimulus values. J Neurophysiol 104:1068-1076.
  • Bromberg-Martin ES, Hikosaka O, Nakamura K (2010a) Coding of task reward value in the dorsal raphe nucleus. J Neurosci 30:6262-6272.
  • Yugeta A, Terao Y, Fukuda H, Hikosaka O, Yokochi F, Okiyama R, Taniguchi M, Takahashi H, Hamada I, Hanajima R, Ugawa Y (2010) Effects of STN stimulation on the initiation and inhibition of saccade in Parkinson disease. Neurology 74:743-748.
  • Bromberg-Martin ES, Hikosaka O (2009) Midbrain dopamine neurons signal preference for advance information about upcoming rewards. Neuron 63:119-126.
  • Matsumoto M, Hikosaka O (2009) Two types of dopamine neuron distinctly convey positive and negative motivational signals. Nature 459:837-841.
  • Matsumoto M, Hikosaka O (2009) Representation of negative motivational value in the primate lateral habenula. Nat Neurosci Jan.12 (1):77-84.
  • Hong S, Hikosaka O (2008) The globus pallidus sends reward-related signals to the lateral habenula. Neuron 60:720-729.
  • Bissmarck F, Nakahara H, Doya K, Hikosaka O (2008) Combining Modalities with Different Latencies for Optimal Motor Control. J Cogn Neurosci 20:1966-1979.
  • Isoda M, Hikosaka O (2008) A neural correlate of motivational conflict in the superior colliculus of the macaque. J Neurophysiol 100:1332-1342.
  • Hikosaka O, Isoda M (2008) Brain mechanisms for switching from automatic to controlled eye movements. Prog Brain Res 171:375-382.
  • Matsumoto M, Hikosaka O (2008) Negative motivational control of saccadic eye movement by the lateral habenula. Prog Brain Res 171:399-402.
  • Isoda M, Hikosaka O (2008) Role for subthalamic nucleus neurons in switching from automatic to controlled eye movement. J Neurosci 28:7209-7218.
  • Nakamura K, Matsumoto M, Hikosaka O (2008) Reward-dependent modulation of neuronal activity in the primate dorsal raphe nucleus. J Neurosci 28:5331-5343.
  • Ikeda T, Hikosaka O (2007) Positive and negative modulation of motor response in primate superior colliculus by reward expectation. J Neurophysiol 98: 31633170
  • Matsumoto M, Hikosaka O (2007) Lateral habenula as a source of negative reward signals in dopamine neurons. Nature 447:1111-1115.
  • Isoda M, Hikosaka O (2007) Switching from automatic to controlled action by monkey medial frontal cortex. Nat Neurosci 10:240-248.
  • Kobayashi S, Kawagoe R, Takikawa Y, Koizumi M, Sakagami M, Hikosaka O (2007) Functional differences between macaque prefrontal cortex and caudate nucleus during eye movements with and without reward. Exp Brain Res 176:341-355.
  • Ding L, Hikosaka O (2007) Temporal Development of Asymmetric Reward-Induced Bias in Macaques. J Neurophysiol 97:57-61.
  • Nakamura K, Hikosaka O (2006) Facilitation of saccadic eye movements by postsaccadic electrical stimulation in the primate caudate. J Neurosci 26:12885-12895.
  • Nakahara H, Nakamura K, Hikosaka O (2006) Extended LATER model can account for trial-by-trial variability of both pre- and post-processes. Neural Netw 19:1027-1046.
  • Kobayashi S, Nomoto K, Watanabe M, Hikosaka O, Schultz W, Sakagami M (2006) Influences of rewarding and aversive outcomes on activity in macaque lateral prefrontal cortex. Neuron 51:861-870.
  • Watanabe K, Ikeda H, Hikosaka O (2006) Effects of explicit knowledge of workspace rotation in visuomotor sequence learning. Exp Brain Res 174:673-678.
  • Ding L, Hikosaka O (2006) Comparison of reward modulation in the frontal eye field and caudate of the macaque. J Neurosci 26:6695-6703.
  • Nakamura K, Hikosaka O (2006) Role of dopamine in the primate caudate nucleus in reward modulation of saccades. J Neurosci 26:5360-5369.
  • Watanabe K, Hikosaka O (2005) Immediate changes in anticipatory activity of caudate neurons associated with reversal of position-reward contingency. J Neurophysiol 94:1879-1887.
  • Takikawa Y, Kawagoe R, Hikosaka O (2004) A possible role of midbrain dopamine neurons in short- and long-term adaptation of saccades to position-reward mapping. J Neurophysiol 92:2520-2529.
  • Kawagoe R, Takikawa Y, Hikosaka O (2004) Reward-predicting activity of dopamine and caudate neurons - a possible mechanism of motivational control of saccadic eye movement. J Neurophysiol 91:1013-1024.
  • Nakahara H, Itoh H, Kawagoe R, Takikawa Y, Hikosaka O (2004) Dopamine neurons can represent context-dependent prediction error. Neuron 41:269-280.
  • Nomura Y, Fukuda H, Terao Y, Hikosaka O, Segawa M (2003) Abnormalities of voluntary saccades in Gilles de la Tourette’s syndrome: pathophysiological consideration. Brain Dev 25 Suppl 1:S48-54.
  • Watanabe K, Lauwereyns J, Hikosaka O (2003) Neural correlates of rewarded and unrewarded eye movements in the primate caudate nucleus. J Neurosci 23:10052-10057.
  • Ikeda T, Hikosaka O (2003). Reward-dependent gain and bias of visual responses in primate superior colliculus. Neuron 39: 693-700.
  • Sakai K, Kitaguchi K, Hikosaka O (2003) Chunking during human visuomotor sequence learning. Exp Brain Res 152:229-242.
  • Watanabe K, Lauwereyns J, Hikosaka O (2003) Effects of motivational conflicts on visually elicited saccades in monkeys. Exp Brain Res 152:361-367.
  • Itoh H, Nakahara H, Hikosaka O, Kawagoe R, Takikawa Y, Aihara K (2003) Correlation of Primate Caudate Neural Activity and Saccade Parameters in Reward-Oriented Behavior. J Neurophysiol 89:1774-1783.
  • Hikosaka O, Rand MK, Nakamura K, Miyachi S, Kitaguchi K, Sakai K, Lu X, Shimo Y (2002b) Long-term retention of motor skill in macaque monkeys and humans. Exp Brain Res 147:494-504.
  • Miyachi S, Hikosaka O, Lu X (2002) Differential activation of monkey striatal neurons in the early and late stages of procedural learning. Exp Brain Res 146:122-126.
  • Lauwereyns J, Watanabe K, Coe B, Hikosaka O (2002) A neural correlate of response bias in monkey caudate nucleus. Nature 418:413-417.
  • Coe B, Tomihara K, Matsuzawa M, Hikosaka O (2002) Visual and Anticipatory Bias in Three Cortical Eye Fields of the Monkey during an Adaptive Decision-Making Task. J Neurosci 22:5081-5090.
  • Lu X, Matsuzawa M, Hikosaka O (2002) A neural correlate of oculomotor sequences in supplementary eye field. Neuron 34:317-325.
  • Nakahara H, Amari Si S, Hikosaka O (2002) Self-organization in the basal ganglia with modulation of reinforcement signals. Neural Comput 14:819-844.
  • Sato M, Hikosaka O (2002) Role of primate substantia nigra pars reticulata in reward-oriented saccadic eye movement. J Neurosci 22:2363-2373.
  • Kobayashi S, Lauwereyns J, Koizumi M, Sakagami M, Hikosaka O (2002) Influence of reward expectation on visuospatial processing in macaque lateral prefrontal cortex. J Neurophysiol 87:1488-1498.
  • Takikawa Y, Kawagoe R, Hikosaka O (2002a) Reward-dependent spatial selectivity of anticipatory activity in monkey caudate neurons. Journal of Neurophysiology 87:508-515.
  • Lauwereyns J, Takikawa Y, Kawagoe R, Kobayashi S, Koizumi M, Coe B, Sakagami M, Hikosaka O (2002) Feature-based anticipation of cues that predict reward in monkey caudate nucleus. Neuron 33:463-473.
  • Takikawa Y, Kawagoe R, Itoh H, Nakahara H, Hikosaka O (2002b) Modulation of saccadic eye movements by predicted reward outcome. Experimental Brain Research 142:284-291.
  • Nakahara H, Doya K, Hikosaka O (2001) Parallel cortico-bsal ganglia mechanisms for acquisition and execution of visuomotor seqeunces - A computational approach. Journal of Cognitive Neuroscience 13: 1-22.
  • Sakagami M, Tsutsui K-I, Lauwereyns J, Koizumi M, Kobayashi S, Hikosaka O (2001) A code for behavioral inhibition on the basis of color, but not motion, in ventrolateral prefrontal cortex of macaque monkey. J Neurosci 21: 4801-4808
  • Lauwereyns J, Sakagami M, Tsutsui K-I, Kobayashi S, Koizumi M, Hikosaka O (2001) Responses to task-irrelevant visual features by primate prefrontal neurons. J Neurophysiol 86: 2001-2010.
  • Shimo Y, Hikosaka O (2001) Role of tonically active neurons in primate caudate in reward-oriented saccadic eye movement. J Neurosci 21: 7804-7814.
  • Lauwereyns J, Koizumi M, Sakagami M, Hikosaka O, Kobayashi S, Tsutsui K (2000) Interference from irrelevant features on visual discrimination by macaques (Macaca fuscata)  a behavioral analogue of human stroop effect. Journal of Experimental Psychology: Animal Behavior Processes 26: 352-357.
  • Rand MK, Hikosaka O, Miyachi S, Lu X, Nakamura K, Kitaguchi K, Shimo Y (2000) Characteristics of sequential movements during early learning period in monkeys. Exp Brain Res 131: 293-304.
  • Sakai K, Hikosaka O, Takino R, Miyauchi S, Nielsen M, Tamada T (2000) What and when: parallel and convergent processing in motor control. J Neurosci 20: 2691-2700.
  • Sakai K, Hikosaka O, Miyauchi S, Sasaki Y, Fujimaki N, Ptz B (1999) Pre-SMA activation during sequence learning reflects visuo-motor association. J Neurosci 19:RC1: 1-6.
  • Nakamura K, Sakai K, Hikosaka O (1999) Effects of local inactivation of monkey medial frontal cortex in learning of sequential procedures. J Neurophysiol 82: 1063-1068.
  • Sakai K, Hikosaka O, Miyauchi S, Takino R, Tamada T, Iwata NK, Nielsen M (1999) Neural representation of a rhythm depends on its interval ratio. J Neurosci 19: 10074-10081.
  • Lu X, Hikosaka O, Miyachi S (1998) Role of monkey cerebellar nuclei in skill for sequential movement. J Neurophysiol 79: 2245-2254.
  • Nakamura K, Sakai K, Hikosaka O (1998) Neuronal activity in medial frontal cortex during learning of sequential procedures. J Neurophysiol 80: 2671-2687.
  • Kawagoe R, Takikawa Y, Hikosaka O (1998) Expectation of reward modulates cognitive signals in the basal ganglia. Nat Neurosci 5: 411-416.
  • Rand MK, Hikosaka O, Miyachi S, Lu X, Miyashita K (1998) Characteristics of a long-term procedural skill in the monkey. Exp Brain Res 118: 293-297.
  • Sakai K, Hikosaka O, Miyauchi S, Takino R, Sasaki Y, Ptz B (1998a) Transition of brain activation from frontal to parietal areas in visuo-motor sequence learning. J Neurosci 18: 1827-1840.
  • Sakai K, Takino R, Hikosaka O, Miyauchi S, Sasaki Y, Ptz B, Fujimaki N (1998b) Separate cerebellar areas for motor control. NeuroReport 9: 2359-2363.
  • Takikawa Y, Kawagoe R, Miyashita N, Hikosaka O (1998) Presaccadic omnidirectional burst activity in the basal interstitial nucleus in the monkey cerebellum. Exp Brain Res 121: 442-450.
  • Terao Y, Fukuda H, Ugawa Y, Hikosaka O, Hanajima R, Furubayashi T, Sakai K, Miyauchi S, Sasaki Y, Kanazawa I (1998) Visualization of the information flow through human oculomotor cortical regions by transcranial magnetic stimulation. J Neurophysiol 80: 936-946.
  • Horikawa HPM, Nakazato T, Hikosaka O (1997) Duration of catalepsy correlates with increased intrastriatal sulpiride. European Journal of Pharmacology 326: 15-21.
  • Miyachi S, Hikosaka O, Miyashita K, Kardi Z, Rand MK (1997b) Differential roles of monkey striatum in learning of sequential hand movement. Exp Brain Res 115: 1-5.
  • Nakahara H, Doya K, Hikosaka O, Nagano S (1997b) Multiple representations in the basal ganglia loops for sequential decision making. Technical Report of IEICE NC97-24: 97-104.
  • Shimojo S, Miyauchi S, Hikosaka O (1997) Visual motion sensation yielded by non-visually driven attention. Vision Res 37: 1575-1580.
  • Hikosaka O, Sakai K, Miyauchi S, Takino R, Sasaki Y, Ptz B (1996) Activation of human presupplementary motor area in learning of sequential procedures: A functional MRI study. J Neurophysiol 76: 617-621.
  • Kojima J, Matsumura M, Togawa M, Hikosaka O (1996) Tonic activity during visuo-oculomotor behavior in the monkey superior colliculus. Neurosci Res 26: 17-28.
  • Miyashita K, Rand MK, Miyachi S, Hikosaka O (1996a) Anticipatory saccades in sequential procedural learning in monkeys. J Neurophysiol 76: 1361-1366.
  • Miyashita N, Hikosaka O (1996) Minimal synaptic delay in the saccadic output pathway of the superior colliculus studied in awake monkey. Exp Brain Res 112: 187-196.
  • Hikosaka O, Rand MK, Miyachi S, Miyashita K (1995b) Learning of sequential movements in the monkey - Process of learning and retention of memory. J Neurophysiol 74: 1652-1661.
  • Iwamura Y, Tanaka M, Hikosaka O, Sakamoto M (1995) Postcentral neurons of alert monkeys activated by the contact of the hand with objects other than the monkey’s own body. Neurosci Lett 186: 127-130.
  • Kato M, Miyashita N, Hikosaka O, Matsumura M, Usui S, Kori A (1995) Eye movements in monkeys with local dopamine depletion in the caudate nucleus. I. Deficits in spontaneous saccades. J Neurosci 15: 912-927.
  • Kori A, Miyashita N, Kato M, Hikosaka O, Usui S, Matsumura M (1995) Eye movements in monkeys with local dopamine depletion in the caudate nucleus. II. Deficits in voluntary saccades. J Neurosci 15: 928-941.
  • Miyashita N, Hikosaka O, Kato M (1995b) Visual hemineglect induced by unilateral striatal dopamine deficiency in monkeys. NeuroReport 6: 1257-1260.
  • Hikosaka O, Miyauchi S, Shimojo S (1993c) Focal visual attention produces illusory temporal order and motion sensation. Vision Res 33: 1219-1240.
  • Hikosaka O, Miyauchi S, Shimojo S (1993e) Voluntary and stimulus-induced attention detected as motion sensation. Perception 22: 517-526.
  • Hikosaka O, Sakamoto M, Miyashita N (1993f) Effects of caudate nucleus stimulation on substantia nigra cell activity in monkey. Exp Brain Res 95: 457-472.
  • Iwamura Y, Tanaka M, Sakamoto M, Hikosaka O (1993) Rostrocaudal gradients in the neuronal receptive field complexity in the finger region of the alert monkey’s postcentral gyrus. Exp Brain Res 92: 360-368.
  • Matsumura M, Kojima J, Gardiner TW, Hikosaka O (1992) Visual and oculomotor functions of monkey subthalamic nucleus. J Neurophysiol 67: 1615-1632.
  • Usui S, Fukuda H, Hikosaka O (1990a) Spontaneous saccades in MPTP-induced hemi-parkinsonian monkeys. Clin Neurol 30: 1181-1189.
  • Hikosaka O, Sakamoto M, Usui S (1989a) Functional properties of monkey caudate neurons. I. Activities related to saccadic eye movements. J Neurophysiol 61: 780-798.
  • Hikosaka O, Sakamoto M, Usui S (1989b) Functional properties of monkey caudate neurons. II. Visual and auditory responses. J Neurophysiol 61: 799-813.
  • Hikosaka O, Sakamoto M, Usui S (1989c) Functional properties of monkey caudate neurons. III. Activities related to expectation of target and reward. J Neurophysiol 61: 814-832.
  • Sakamoto M, Hikosaka O (1989) Eye movements induced by microinjection of GABA agonist in the rat substantia nigra pars reticulata. Neurosci Res 6: 216-233.
  • Hikosaka O, Sakamoto M (1987) Dynamic characteristics of saccadic eye movements in the albino rat. Neurosci Res 4: 304-308.
  • Hikosaka O, Wurtz RH (1986) Saccadic eye movements following injection of lidocaine into the superior colliculus. Exp Brain Res 61: 531-539.
  • Hikosaka O, Sakamoto M (1986a) Cell activity in monkey caudate nucleus preceding saccadic eye movements. Exp Brain Res 63: 659-662.
  • Hikosaka O, Sakamoto M (1986b) Neural activities in the monkey basal ganglia related to attention, memory and anticipation. Brain Dev 8: 454-462.
  • Hikosaka O, Wurtz RH (1985a) Modification of saccadic eye movements by GABA-related substances. I. Effect of muscimol and bicuculline in the monkey superior colliculus. J Neurophysiol 53: 266-291.
  • Hikosaka O, Wurtz RH (1985b) Modification of saccadic eye movements by GABA-related substances. II. Effects of muscimol in monkey substantia nigra pars reticulata. J Neurophysiol 53: 292-308.
  • Hikosaka O, Tanaka M, Sakamoto M, Iwamura Y (1985) Deficits in manipulative behaviors induced by local injections of muscimol in the first somatosensory cortex of the conscious monkey. Brain Res 325: 1-2.
  • Iwamura Y, Tanaka M, Sakamoto M, Hikosaka O (1985b) Diversity in receptive field properties of vertical neuronal arrays in the crown of the postcentral gyrus of the conscious monkey. Exp Brain Res 58: 400-411.
  • Iwamura Y, Tanaka M, Sakamoto M, Hikosaka O (1985d) Vertical neuronal arrays in the postcentral gyrus signaling active touch: A receptive field study in the conscious monkey. Exp Brain Res 58: 412-420.
  • Hikosaka O, Wurtz RH (1983a) Effects on eye movements of a GABA agonist and antagonist injected into monkey superior colliculus. Brain Res 272: 368-372.
  • Hikosaka O, Wurtz RH (1983b) Visual and oculomotor functions of monkey substantia nigra pars reticulata. I. Relation of visual and auditory responses to saccades. J Neurophysiol 49: 1230-1253.
  • Hikosaka O, Wurtz RH (1983c) Visual and oculomotor functions of monkey substantia nigra pars reticulata. II. Visual responses related to fixation of gaze. J Neurophysiol 49: 1254-1267.
  • Hikosaka O, Wurtz RH (1983d) Visual and oculomotor functions of monkey substantia nigra pars reticulata. III. Memory-contingent visual and saccade responses. J Neurophysiol 49: 1268-1284.
  • Hikosaka O, Wurtz RH (1983e) Visual and oculomotor functions of monkey substantia nigra pars reticulata. IV. Relation of substantia nigra to superior colliculus. J Neurophysiol 49: 1285-1301.
  • Iwamura Y, Tanaka M, Sakamoto M, Hikosaka O (1983a) Converging patterns of finger representation and complex response properties of neurons in area 1 of the first somatosensory cortex of the conscious monkey. Exp Brain Res 51: 327-337.
  • Iwamura Y, Tanaka M, Sakamoto M, Hikosaka O (1983b) Functional subdivisions representing different finger regions in area 3 of the first somatosensory cortex of the conscious monkey. Exp Brain Res 51: 315-326.
  • Hikosaka O, Igusa Y (1980) Axonal projection of prepositus hypoglossi and reticular neurons in the brainstem of the cat. Exp Brain Res 39: 441-451.
  • Hikosaka O, Igusa Y, Imai H (1980a) Inhibitory connections of nystagmus-related reticular burst neurons with neurons in the abducens, prepositus hypoglossi and vestibular nuclei in the cat. Exp Brain Res 39: 301-311.
  • Hikosaka O, Nakao S, Shimazu H (1980b) Postsynaptic inhibition underlying spike suppression of secondary vestibular neurons during quick phases of vestibular nystagmus. Neurosci Lett 16: 21-26.
  • Ishimine S, Hikosaka O, Nakamura Y (1980) Spatio-temporal patterns of pre- and postsynaptic inhibition induced by primary afferent activation in the trigeminal sensory nucleus in cats. Exp Brain Res 40: 154-163.
  • Iwamura Y, Tanaka M, Hikosaka O (1980) Overlapping representation of fingers in area 2 of the monkey somatosensory cortex of the conscious monkey. Brain Res 197: 516-520.
  • Hikosaka O, Igusa Y, Imai H (1978a) Firing pattern of prepositus hypoglossi and adjacent reticular neurons related to vestibular nystagmus in the cat. Brain Res 144: 395-403.
  • Hikosaka O, Igusa Y, Nakao S, Shimazu H (1978b) Direct inhibitory synaptic linkage of pontomedullary reticular burst neurons with abducens motoneurons in the cat. Exp Brain Res 33: 337-352.
  • Hikosaka O, Maeda M, Nakao S, Shimazu H, Shinoda Y (1977) Presynaptic impulses in the abuducens nucleus and their relation to postsynaptic potentials in motoneurons during vestibular nystagmus. Exp Brain Res 27: 355-376.
  • Hikosaka O, Kawakami T (1977) Inhibitory reticular neurons related to the quick phase of vestibular nystagmus - their location and projection. Exp Brain Res 27: 377-396.
  • Hikosaka O, Kawakami T (1976) Inhibitory interneurons in the reticular formation and their relation to vestibular nystagmus. Brain Res 117: 513-518.
  • Hikosaka O, Maeda M (1973) Cervical effects on abducens motoneurons and their interaction with vestibulo-ocular reflex. Exp Brain Res 18: 512-530.

Reviews

Bromberg-Martin ES, Matsumoto M, Hikosaka O (2010) Dopamine in motivational control: rewarding, aversive, and alerting. Neuron 68:815-834.

Hikosaka O (2010) The habenula: from stress evasion to value-based decision-making. Nat Rev Neurosci 11:503-513.

Hikosaka O, Isoda M (2010) Switching from automatic to controlled behavior: cortico-basal ganglia mechanisms. Trends Cogn Sci 14: 154-161.

Hikosaka O, Sesack SR, Lecourtier L, Shepard PD (2008) Habenula: crossroad between the basal ganglia and the limbic system. J Neurosci 28:11825-11829.

Hikosaka O, Bromberg-Martin E, Hong S, Matsumoto M (2008) New insights on the subcortical representation of reward. Curr Opin Neurobiol 18:203-208.

Hikosaka O (2008) [Decision-making and learning by cortico-basal ganglia network]. Brain Nerve 60:799-813.

Balleine BW, Delgado MR, Hikosaka O (2007) The role of the dorsal striatum in reward and decision-making. J Neurosci 27:8161-8165.

Hikosaka O (2007) Basal Ganglia Mechanisms of Reward-oriented Eye Movement. Ann N Y Acad Sci 1104:229-249.

Hikosaka O (2007) Habenula. Scholarpedia 2:2703. http://www.scholarpedia.org/article/Habenula

Hikosaka O (2007) GABAergic output of the basal ganglia. Prog Brain Res 160:209-226.

Hikosaka O, Nakamura K, Nakahara H (2006) Basal Ganglia orient eyes to reward. J Neurophysiol 95:567-584.

Sakai K, Hikosaka O, Nakamura K (2004) Emergence of rhythm during motor learning. Trends Cogn Sci 8:547-553.

Donoghue JP, Hikosaka O (2003) Motor systems. Curr Opin Neurobiol 13:643-646.

Hikosaka O (2002) A new approach to the functional systems of the brain. Epilepsia 43 Suppl 9:9-15.

Hikosaka O, Nakamura K, Sakai K, Nakahara H (2002) Central mechanisms of motor skill learning. Curr Opin Neurobiol 12: 217222.

Hikosaka O, Takikawa Y, Kawagoe R (2000) Role of the basal ganglia in the control of purposive saccadic eye movements. Physiol. Rev. 80: 953-978.

Hikosaka O, Sakai K, Nakahara H, Lu X, Miyachi S, Nakamura K, Rand MK (1999) Neural mechanisms for learning of sequential procedures. In: The New Cognitive Neurosciences (Gazzaniga MS, eds), pp. 553-572, Cambridge, MA: The MIT Press.

Hikosaka O, Nakahara H, Rand MK, Sakai K, Lu X, Nakamura K, Miyachi S, Doya K (1999) Parallel neural networks for learning sequential procedures. Trends Neurosci 22: 464-471.

Hikosaka O (1999) Probing consciousness with an electrode. Brain Res Bull 50: 337-338.

Hikosaka O (1998b) Neural systems for control of voluntary action - a hypothesis. Advances in Biophysics 35: 81-102.

Hikosaka O, Miyashita K, Miyachi S, Sakai K, Lu X (1998) Differential roles of the frontal cortex, basal ganglia, and cerebellum in visuomotor sequence learning. Neurobiology of Learning and Memory 70: 137-149.

Hikosaka O, Miyauchi S, Shimojo S (1996e) Orienting of spatial attention - its reflexive, compensatory, and voluntary mechanisms. Cognitive Brain Research 5: 1-9.

Hikosaka O, Miyauchi S, Takeichi H, Shimojo S (1996f) Multimodal spatial attention visualized by motion illusion. In: Attention and Performance XVI  Information Integration in Perception and Communication (Inui T, McClelland J, eds), pp. 237-261. Cambridge, MA: MIT Press.

Hikosaka O, Miyauchi S, Shimojo S (1993d) Visual attention revealed by an illusion of motion. Neurosci Res 18: 11-18.

Hikosaka O (1991a) Basal ganglia - possible role in motor coordination and learning. Curr Opin Neurobiol 1: 638-643.

Hikosaka O (1989c) Role of basal ganglia in saccades. Rev Neurol (Paris) 145: 580-586.

Evarts EV, Kimura M, Wurtz RH, Hikosaka O (1984) Behavioral correlates of activity in basal ganglia neurons. Trends Neurosci 7: 447-453.

Book sections

Hikosaka O (2009) Basal Ganglia and Oculomotor Control. In: Squire LR (ed.)Encyclopedia of Neuroscience, volume 2, pp. 53-61. Oxford: Academic Press.

Nomura Y., Fukuda H., Terao Y., Hikosaka O., Segawa M. (2003) Abnormalities of voluntary saccades in Gilles de la Tourette’s syndrome: pathophysiological consideration. Brain Dev 25 Suppl 1: S48-54.

Shimojo S., Hikosaka O., Miyauchi S. (In press) Automatic and controlled processes of attention revealed in the line motion effect. In: Attention & Performance XV (Gopher D, Koirat A, eds), pp. Cambridge, MA: MIT Press.

Hikosaka O., Sakai K., Nakahara H., Lu X., Miyachi S., Nakamura K., Rand M.K. (1999) Neural mechanisms for learning of sequential procedures. In: The Cognitive Neurosciences (Gazzaniga MS, eds), pp. 553-572. Cambridge, MA: The MIT Press.

Hikosaka O., Miyachi S., Miyashita K., Rand M.K. (1996a) Learning of sequential procedures in monkeys. In: The Acquisition of Motor Behavior in Vertebrates (Bloedel JR, Ebner TJ, Wise SP, eds), pp. 303-317. Cambridge, MA: The MIT Press.

Hikosaka O., Miyachi S., Miyashita K., Rand M.K., Karadi Z. (1996b) Procedural learning in monkeys - possible roles of the basal ganglia. In: Perception, Memory, and Emotion: Frontier in Neuroscience (Ono T, McNaughton BL, Molotchnikoff S, Rolls ET, Nishijo H, eds), pp. 403-420. Oxford, UK: Elsevier.

Hikosaka O., Miyachi S., Miyashita K., Sakai K., Miyauchi S., Takino R., Sasaki Y., Ptz B. (1996c) Neural mechanisms of sequential procedural learning. In: Integrative and Molecular Approach to Brain Function (Ito M, Miyashita Y, eds), pp. 285-292. Amsterdam: Elsevier.

Hikosaka O., Miyashita K., Sakai K., Miyauchi S., Takino R., Sasaki Y., Ptz B. (1996d) Role of the medial frontal cortex in sequential procedural learning. In: Brain Processes and Memory (Ishikawa K, McGaugh JL, Sakata H, eds), pp. 299-306. Amsterdam: Elsevier.

Hikosaka O., Rand M.K., Miyashita K., Miyachi S. (1996g) Learning of sequential procedures in monkeys. In: Recent Advances in Clinical Neurophysiology (Kimura J, Shibasaki H, eds), pp. 296-303. Amsterdam: Elsevier.

Hikosaka O., Sakai K., Miyauchi S., Takino R., Sasaki Y., Ptz B. (1996j) Brain activation during learning of sequential procedures. In: Visualization of Information Processing in the Human Brain: Recent Advances in MEG and Functional MRI (Hashimoto I, Okada YC, Ogawa S, eds), pp. 245-252. Amsterdam: Elsevier.

Segawa M., Tanaka R., Nomura Y., Fukuda H., Hikosaka O. (1996) Saccadic eye movements in basal ganglia disorders. In: Recent Advances in Clinical Neurophysiology (Kimura J, Shibasaki H, eds), pp. 170-176. Amsterdam: Elsevier.

Shimojo S., Tanaka Y., Hikosaka O., Miyauchi S. (1996) Vision, attention, and action: Inhibition and facilitation in sensory-motor links revealed by the reaction time and the line motion. In: Attention and Performance XVI  Information Integration in Perception and Communication (Inui T, McClelland J, eds), pp. 597-630. Cambridge, MA: MIT Press.

Hikosaka O. (1995) Neural mechanisms of saccadic eye movement. In: Vertigo, Nausea, tinnitus and Hearing Loss in Central and Peripheral Vestibular Diseases. Proceedings of the XXIInd Annual Meeting of the International Neurootological and Equilibriometric Society. (Claussen C-F, Sakata E, Itoh A, eds), pp. 3-18. Amsterdam: Elsevier.

Hikosaka O., Fukuda H., Segawa M., Nomura Y. (1995a) Voluntary saccades in normal and in dopamine deficient subjects. In: Age-Related Dopamine-Deficient Disorders (Segawa M, Nomura Y, eds), pp. 59-68. Basal: Karger.

Hikosaka O., Rand M.K., Miyachi S,. Miyashita K. (1995c) Procedural learning in the monkey. In: Functions of the Cortico-Basal Ganglia Loop (Kimura M, Graybiel AM, eds), pp. 18-30. Tokyo: Springer.

Kato M., Hikosaka O. (1995) Function of the indirect pathway in the basal ganglia oculomotor system: visuo-oculomotor activities of external pallidum neurons. In: Age-Related Dopamine-Deficient Disorders (Segawa M, Nomura Y, eds), pp. 178-187. Basal: Karger.

Hikosaka O. (1994) Role of basal ganglia in control of innate movements, learned behavior and cognition - a hypothesis. In: The Basal Ganglia IV: New Ideas and Data on Structure and Function (Percheron G, McKenzie JS, Fger J, eds), pp. 589-596. New York: Plenum Press.

Segawa M., Hikosaka O., Fukuda H., Uetake K. (1994) Deficits in saccadic eye movements in basal ganglia disorders. In: The Basal Ganglia IV: New Ideas and Data on Structure and Function (Percheron G, McKenzie JS, Feger J, eds), pp. 525-531. New York: Plenum Press.

Hikosaka O., Matsumura M., Kojima J., Gardiner T.W. (1993b) Role of basal ganglia in initiation and suppression of saccadic eye movements. In: Role of the Cerebellum and Basal Ganglia in Voluntary Movement (Mano N, Hamada I, DeLong MR, eds), pp. 213-219. Amsterdam: Elsevier.

Hikosaka O. (1993) Role of the basal ganglia in motor learning: a hypothesis. In: Brain Mechanisms of Perception and Memory (Ono T, Squire LR, Raichle ME, PerrettD.I., Fukuda M, eds), pp. 497-513. New York: Oxford University Press.

Hikosaka O., Fukuda H., Kato M., Uetake K., Nomura Y., Segawa M. (1993a) Deficits in saccadic eye movements in hereditary progressive dystonia with marked diurnal fluctuation. In: Hereditary Progressive Dystonia with Marked Diurnal Fluctuation (Segawa M, eds), pp. 159-177. Lancs & New York: The Parthenon Publishing Group.

Hikosaka O., Imai H., Segawa M. (1992) Saccadic eye movements in parkinsonism. In: Vestibular and Brain Stem Control of Eye, Head and Body Movements (Shimazu H, Shinoda Y, eds), pp. 405-414. Tokyo: Japan Scientific Society Press.

Hikosaka O. (1991b) Role of the forebrain in oculomotor function. In: Role of the Forebrain in Sensation and Behavior (Holstege G, eds), pp. 101-107. Amsterdam: Elsevier.

Hikosaka O. (1989a) Motor programming in basal ganglia. In: Neural Programming (Ito M, eds), pp. 101-109. Tokyo: Japan Scientific Societies Press.

Hikosaka O. (1989b) Role of basal ganglia in initiation of voluntary movements. In: Dynamic Interactions in Neural Networks: Models and Data (Arbib MA, Amari S, eds), pp. 153-167. New York: Springer-Verlag.

Hikosaka O., Wurtz R.H. (1989) The basal ganglia. In: The Neurobiology of Saccadic Eye Movements (Wurtz RH, Goldberg ME, eds), pp. 257-281. Amsterdam: Elsevier.

Hikosaka O., Segawa M., Imai H. (1987) Voluntary saccadic eye movement: application to analyze basal ganglia disease. In: Highlights in Neuro-Ophthalmology (Ishikawa S, eds), pp. 133-138. Amsterdam: Aeolus Press.

Nomura Y., Segawa M., Soda M., Hikosaka O. (1987) Voluntary saccadic eye movements in basal ganglia disorders. In: Highlights in Neuro-Ophtha