NNRL Researchers get recognition at NEI Focus on Fellows 2022
NNRL researchers got recognized at the annual NEI Focus on Fellows 2022. Congratulations to Laura, Jayshree, Mohita, Daniel and Kamil!
NNRL Celebrates Diwali 2022
NNRL celebrated Diwali 2022 with Indian foods and traditional lamps. Diwali is the festival of light, a fitting celebration for our lab focused on photoreceptors!
Jaya Krishnan joins NNRL as a staff scientist
Jaya Krishnan, PhD has joined NNRL as a staff scientist. Dr. Krishnan completed her PhD with Dr. Rakesh Mishra at the Centre for Cellular and Molecular Biology in Hyderabad, India. Before coming to NIH, Dr. Krishnan worked with Dr. Nicolas Rohner at Stowers Institute in Kansas City studying metabolic adaptation in cavefish. Welcome Dr. Krishnan!
NNRL runs NEI 5K 2022
Several members of NNRL ran and others cheered for NEI Walk/Run/Roll 5K.
NNRL research appears in headlines
NNRL researchers Claire Marchal, Nivedita Singh, Zachary Batz, Jayshree Advani, Catherine Jaeger, Ximena Corso-Diaz led by Anand Swaroop, mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell’s nucleus. The resulting comprehensive gene regulatory network provides insights into regulation of gene expression in general, and in retinal function, in both rare and common eye diseases. The study is now published in Nature Communications. More details: https://www.nei.nih.gov/about/news-and-events/news/3d-map-reveals-dna-organization-within-human-retina-cells and Video highlight NEI made for the Hi-C paper.
Eunyoo Kim joins Center for Retinal Diseases & Surgery as Ophthalmic Technician
NNRL researcher Dr. Eunyoo Kim joined Center for Retinal Diseases & Surgery as an Ophthalmic Technician. Thank you for all your contributions to NNRL and best wishes in the new role!
Soumitra Pal joins NNRL as a staff scientist
Soumitra Pal, PhD has joined NNRL as a Staff Scientist. Before joining the lab, Dr. Pal earned a Ph.D. from the Indian Institute of Technology (Mumbai, India) in the lab of Professor Abhiram Ranade. Most recently, Dr. Pal worked with Dr. Teresa Pryztycka at NCBI. Welcome Dr. Pal!
Trupti Shetty joins Harvard-MIT Center for Regulatory Science
NNRL researcher Dr. Trupti Shetty joined Harvard-MIT Center for Regulatory Science as a Research Fellow. Thank you for all your contributions to NNRL and best wishes in the new role!
Holly Chen joins UAB as assistant professor
NNRL researcher Dr. Holly Chen joined University of Alabama at Birmingham as an Assistant Professor. Congratulations to Dr. Chen on her new appointment, we will miss you at NNRL!
Madison Luce & Fares Siddig join NNRL as postbacs
Madison Luce from Northwestern University and Fares Siddig from the University of Michigan have joined NNRL post-baccalaureates. Welcome!
Summer party @ NNRL
Drs. Manju and Anand Swaroop hosted a summer party to thank our NEI/NIH colleagues (with family). Due to the pandemic, this is the first time the annual party has been held since 2019. The party included many NNRL collaborators, colleagues, and families. We also used the occasion to say farewell to lab members and welcome new colleagues.
Daniel Brock to join MD/PhD program at Baylor
NNRL postbac researcher Daniel Brock joined MD/PhD at Baylor College of Medicine. Thank you for all your contributions to NNRL and good luck with your graduate study!
Coco Jiang joins Cleveland Clinic as project scientist
NNRL researcher Dr. Coco Jiang joined Cleveland Clinic as a Project Scientist. Thank you for all your contributions to NNRL and good luck in the new role!
Anand Swaroop appears on the latest episode of the Stem Cell Report podcast alongside collaborators Mark Humayun and Masayo Takahasio to discuss recent research in regenerative medicine for eye disease. You can hear the podcast here: The Stem Cell Report — Episode 201.
Jayshree Advani and Laura Campello (picture top left and center) participated in Take Your Child to Work Day 2022. They gave future scientists a lesson in extracting DNA from strawberries. NEI also hosted a virtual eyeball dissection and a video on optical illusions.
We held a farewell party to say goodbye to Coco Jiang and Ryan Kelley who are leaving our lab to take on new jobs at the Cleveland Clinic and PTC Therapeutics, respectively. Congratulations to both!
Congratulations to Kamil Kruczek, his recent publication in Stem Cells has been highlighted as a high impact publication by the journal. Read the article here: Stem Cells.
“NEI researchers discover cellular events that precede neurodegenerative eye disease” – a new NEI press piece highlighting work from our lab led by Coco (Ke) Jiang and Anupam Mondal. Read the piece here: NEI news story
Noor White, a former postdoc from our lab and current staff scientist in the NEI Biological Imaging Core, was profiled by the I am Intramural Blog. As a postdoc, White explored the evolution of vision in vertebrates. By uncovering genes crucial to vision, she has shed light on the genetic causes of retinal diseases. Intramural blog post
Congratulations to Lina Zelinger for winning a travel award for outstanding presentation, titled “The message in the non-coding RNAs of the mammalian retina,” at the 41st annual meeting of the Israeli Society for Vision and Eye Research
Congratulations to Michael Power who has taken a job as a Technical Support Scientist at Abbott Pharmaceutical in Ireland!
Congratulations to all the winners of NEI Director’s awards from our lab. Lina Zelinger, Jayshree Advani, and Milton English (top row) received an award For outstanding innovative research in analyzing large families with age-related macular degeneration. Coco Jiang and Jacob Nellissery (middle row) were honored for technical excellence in developing methods for measuring mitochondrial function in the retina tissue ex vivo. Finally, Holly Chen and Kamil Kruczek (bottom row) received an award for outstanding achievements in developing therapies for retinal diseases.
Congratulations to postdoc Anupam Mondal for winning an ODS grant! His proposal was entitled "Modulation of epigenome and cellular pathways in the aging retina by diet and micronutrient suppelmentation."
Congratulations to postdoc Laura Campello-Blasco for winning an ARVO travel award, and postdocs Laura Campello-Blasco, Partha Dey and Nivedita Singh for winning FARE awards from the NIH!
Congratulations to PhD student Michael Phelan! Michael one the Temple University Three Minute Talk Competition!
"Researchers use patients' cells to test gene therapy for rare eye disease"-- a new HHS press piece about research from our lab is available here!
Congratulations to postbac James Gentry! He is heading to start a PhD program at the University of Virginia. James has been a productive member of the NNRL for nearly two years now, and he will be missed. Below is a photo from his farewell zoom party.
A new Seminars in Cell & Developmental Biology publication reviews the genes involved in primary cilia biogenesis and associated retinal ciliopathies (read the publication).
Congratulations to postdoc Dr. Andrew Smith! He is heading to Washington University at St. Louis for a great new postdoc. We will miss him, but we bid him farewell via a lab zoom party!
A new Stem Cells publication "discusses the current status and future potential of combining retinal organoids as human models with recent technologies to advance the development of gene, cell, and drug therapies for retinopathies." Read the publication.
A new Nature publication restores sight in mice by turning skin cells into light-sensing eye cells! "This is the first study to show that direct, chemical reprogramming can produce retinal-like cells, which gives us a new and faster strategy for developing therapies for age-related macular degeneration and other retinal disorders caused by the loss of photoreceptors," said Anand Swaroop (read the publication). Also read the associated NEI press release here, and another press piece available here.
A new Cell Reports publication points to targeting the epigenome as a potentail therapeutic strategy--as detailed in a recent NEI press release (read the press release). This work provides "pivotal connections between aging, the epigenome, dysfunction of the cell’s mitochondria, and diseases such as AMD" (read the publication). Another press piece is available here.
The NNRL RDGT section is keeping in touch during the COVID19 pandemic. We have been holding regular video conferences to update each other on research progress, while maintaining safe physical distance.
NNRL graduate student Michael Phelan is helping the Temple University COVID Assistance Team to design and build 3D-printed molds to make face shields for health workers treating COVID-19 patients. Currently, they are producing hundreds of shields per day. Phelan is a bioengineering Ph.D. student, splitting his time between NEI and Temple. Read the Temple University news article.
A new publication in the journal Alzheimer's and Dementia found that strict adherence to a Mediterranean diet may help preserve cognitive function (read the publication). The study was led by an NEI scientist investigating how nutrition affects the brain and eye (read the NEI press release). Another press piece is available here.
NNRL, and the RDGT section was well represented at the 2019 National Eye Institute Director's awards. Dr. Ximena Corso Diaz won an award for receiving an external research grant (top photo, third from left). A group of NNRL members received an award for technology innovation in the NNRL, including (second photo, starting second from left) Dr. Anupam Mondal, Dr. Noor White, Matthew Brooks, Dr. Koray Kaya. Dr. Jacob Nellissery (third photo) won an award for administrative and technical excellence. Additionally, Dr. Holly Chen received the rising star award. Congratulations to all!
A new Journal of Clinical Investigation publication discuses the role of single-strand binding protein 1 in the formation of optic nerve connections and the resulting impact for patients (read the publication).
Congratulations to postdocs Dr. Ryan Kelley and Dr. Laura Campello for winning best 10-minute talk and runner-up best 3-minute talk (respectively) at this year's Focus on Fellows event, hosted by the National Eye Institute!
A new Translational Science of Rare Diseases publication reviews the biology of photoreceptor cilia and associated defects and discusses recent progress in evolving treatment modalities, especially using patient-derived iPSCs, for retinal ciliopathies (read the publication).
Several members of the RDGT section attended the Cell Symposium: Transcriptional Regulation in Evolution, Development, Disease in Chicago, IL, and presented their work there.
Postdoctoral fellow Dr. Andrew Smith presented at the 2019 NHLBI Mitochondrial Biology Symposium. His poster was entitled "DJ-1 Like Protein GATD3A is a Mitochondrial Amidotransferase."
Congratulations to postdoctoral fellow Dr. Noor White (second from left) who placed third among 14 competitors at the NIH Three-minute Talk Competition! Her presentation was entitled “An Evolutionary Perspective on Visual Disease”.
The NNRL held its 3rd Annual Research Retreat on Friday, June 14th. The all-day symposium featured talks by NNRL members, as well as two keynote talks from speakers outside of the National Eye Institute, and a lunch-and-learn session on grant writing and PI-track opportunities within the NIH. The retreat was followed by a party at NNRL chief Dr. Anand Swaroop's home. Congratulations to postdocs Noor White, Holly Chen, Ryan Kelly and postbac Rebecca Lees for winning best 15 minute talks. Congratulations to graduate student Michael Phelan and postdoc Xulong Liang for winning best 5 minute talks.