Search results for "Leber Hereditary Optic neuropathy"

212 items

A Step Closer to Identifying Cause of a Blinding Disease

… a step closer to identifying cause of a blinding disease … researchers find clue to rare genetic disorder may 22 2019 optic nerve disorders basic research grantee leber hereditary optic neuropathy   lhon is an inherited form of vision loss that causes people to have trouble with their colour …

Clinical Trial Uses Gene Therapy to Target Mutations in Mitochondrial Genes

… bascom palmer eye institute of the university of miami miller school of medicine has pioneered a gene therapy approach for leber hereditary optic neuropathy lhon an inherited genetic disorder that causes rapid permanent and bilateral loss of vision in people of all …

Wadih Zein, M.D.

… wadih zein md … wadih zein md … staff clinician … ophthalmic clinical genetics section … research interests … hereditary pediatric eye diseases adult strabismus ophthalmic genetics and visual function … contact information … email … in lebanon he serves as an ophthalmology advisor and member of the scientific board of multiple patient associations for hereditary disease with ocular manifestations dr zein studies hereditary pediatric eye diseases affecting the retina including retinitis pigmentosa leber congenital amaurosis stargardt disease and best disease additionally he investigates systemic hereditary diseases that …

The Eye Clinic: Wadih Zein, M.D.

… visual function at nei dr zein became an nei employee in 2008 and specializes in the care of patients with pediatric and hereditary eye diseases he sees patients  both children and adults with a broad array of ocular and systemic disorders such as achromatopsia albinism aniridia best disease cohen syndrome gyrate atrophy joubert syndrome leber congenital amaurosis methylmalonic acidemia mucolipidosis retinitis pigmentosa stargardt disease and usher syndrome dr … the lives of the patients and the lack of adequate treatment options he is interested in studying the natural history of hereditary eye diseases as well as developing outcome measures to be used in future treatments …

Wadih Zein, M.D.

… pediatric ophthalmology adult strabismus ophthalmic genetics and visual function … current projects … dr zein studies hereditary pediatric eye diseases affecting the retina including retinitis pigmentosa leber congenital amaurosis stargardt disease and best disease additionally he investigates systemic hereditary diseases that can affect the eye such as usher syndrome bardetbiedl syndrome alstrom syndrome joubert syndrome …

Scientists Test New Gene Therapy for Vision Loss From a Mitochondrial Disease

… scientists test new gene therapy for vision loss from a mitochondrial disease … nihfunded study shows success in targeting mitochondrial … approach that can target mtdna in living mice and people their success in creating a mouse model of lhon and using it to test an investigational gene therapy is described today in the proceedings of the national academy of sciences the global …

Report on the National Eye Institute Audacious Goals Initiative: Regenerating the Optic Nerve

… ky 40202  williamguidolouisvilleedu download the national eye institute audacious goals initiative regenerating the optic nerve report pdf 230 kb read the report as published in investigative ophthalmology visual science iovs … abstract … … neurons and neural connections in the eye and visual system this workshop focused on identifying promising strategies for optic nerve regeneration its principal objective was to solicit input on future agirelated funding announcements and … years this report summarizes input from the meeting and serves as guidance for future funding of research that focuses on optic nerve regeneration … introduction … the neis audacious goals initiative agi program initiated in 2012 at that time the …

Ocular Gene Therapy Core

… been conducted for treatment of several inherited retinal diseases ird and have shown promising results in patients with leber congenital amaurosis type 2 lca2 choroideremia and lebers hereditary optic neuropathy lhon to date over 250 genes have been identified as diseasecausing genes for ird and a majority of these …

Optical Illusions

optical header an optical illusion is something that plays tricks on your vision optical illusions teach us how our eyes and brain work together to see you live in a threedimensional world so your brain gets clues about depth shading lighting and position to help you interpret what you see but when you look at a twodimensional image your brain can be fooled because it doesnt get the same clues…

New Models for Eye Disease Research

… replacement cells are working and determine whether the treatment restores vision … retinal ganglion cell replacement in optic neuropathies  ey029903 … principal investigators jeffrey l goldberg stanford university david j calkins vanderbilt … j zack johns hopkins university goldberg and colleagues study glaucoma a condition where progressive degeneration of the optic nerve threatens vision the optic nerve made up of retinal ganglion cell nerve fibers conducts visual information from … models and assess the treatment efficacy … retinal ganglion cell replacement in clinically relevant models of optic neuropathy  ey029893 … principal investigators tonia rex vanderbilt university medical center brian samuels university of …