Colorful microscopy image of optic nerve with nerve fibers and veins

Several research groups funded through the NEI Audacious Goals Initiative (AGI) have developed new imaging tools to see the retina and optic nerve in unprecedented detail. Researchers will be able to go beyond examining anatomy to measuring the cells’ function; asking not only whether the cells and axons look healthy but whether they act healthy. Ultimately, the resulting advanced imaging technologies will be used to test the effects of potential regenerative therapies developed through the AGI.

This virtual symposium will give updates from the five AGI funded teams from the Functional Imaging Consortium. The investigators will talk about their projects and how they intend to distribute them.

Agenda

February 2, 2:00-5:00p EST

Welcome – NEI Director Michael Chiang, M.D.

Background/Intro – Steven Becker, Ph.D., NEI Office of Regenerative Medicine

AGI Imaging Consortia project presentations:

  • Krzysztof Palczewski, Ph.D., University of California, Irvine, & Grazyna Palczewska, Ph.D., Polgenix – A Two-Photon Ophthalmoscope for Human Retinal Imaging and Functional Testing
  • David Williams, Ph.D., University of Rochester – Accelerating Vision Restoration with In Vivo Cellular Imaging of Retinal Function
  • Austin Roorda, Ph.D., University of California, Berkeley – Introducing the Optoretinogram (ORG): Systems for all-optical, noninvasive assessment of structure and function in the living human retina  
  • Sheng-Kwei Song, Ph.D., Washington University in St. Louis – Imaging Optic Nerve Function and Pathology
  • Alfredo Dubra, Ph.D., Stanford University – Platform Technologies from Microscopic Retinal Imaging: Development and Translation & Jessica Morgan, Ph.D., University of Pennsylvania – Platform Technologies for Microscopic Retinal Imaging: Assessing Retinal Function

Reflections and Overview – Leonard A.  Levin, M.D., Ph.D., McGill University (ESOC)

Discussion

Closing Remarks

Contact

Amberlynn Reed
NEI Office of Regenerative Medicine
301-496-2234

Presentations

Krzysztof Palczewski, Ph.D. & Grazyna Palczewska, Ph.D. 

Krzysztof Palczewski, Ph.D., University of California, Irvine
Grazyna Palczewska, Ph.D., Polgenix

A Two-Photon Ophthalmoscope for Human Retinal Imaging and Functional Testing

Transcript of Palczewski/Palczewska presentation

David Williams, Ph.D.

David Williams, Ph.D., University of Rochester

Accelerating Vision Restoration with In Vivo Cellular Imaging of Retinal Function

Transcript of Williams presentation

Austin Roorda, Ph.D.

Austin Roorda, Ph.D., University of California, Berkeley

Introducing the Optoretinogram (ORG): Systems for all-optical, noninvasive assessment of structure and function in the living human retina

Transcript of Roorda presentation

Sheng-Kwei Song, Ph.D.

Sheng-Kwei Song, Ph.D., Washington University in St. Louis

Imaging Optic Nerve Function and Pathology

Transcript of Song presentation

Alfredo Dubra, Ph.D. & Jessica Morgan, Ph.D.

Alfredo Dubra, Ph.D., Stanford University – Platform Technologies from Microscopic Retinal Imaging: Development and Translation

Jessica Morgan, Ph.D., University of Pennsylvania – Platform Technologies for Microscopic Retinal Imaging: Assessing Retinal Function

Transcript of Dubra/Morgan presentation

Audio described versions of these videos are not yet available. If you require an audio described version, please contact Amberlynn Reed at the email address listed above.

Last updated: February 26, 2021