Analysis of samples was performed at the RPE progenitor stage for two key RPE markers – transcription factor MITF and pigmentation enzyme TYRP1

 

iPSC clone name

%MITF positive cells

% TYRP1 positive cells

1

BB0064 CLONE 93

97

87

2

BB0152 CLONE 88

47

56

3

BB0045 CLONE 86

13

36

4

BB00108 CLONE 5

96

84

5

BB0038 CLONE 54

95

22

6

BB0072

NA

NA

7

BB00125 CLONE 53

61

69

8

BB0088 CLONE 22

97

79

9

BB00109 CLONE 64

78

40

10

BB0066 CLONE 423

57

66

11

BB0073 CLONE 13

96

74

Credits: Ruchi Sharma, Devika Bose, Genqing Liang, Roba Dejene, and Kapil Bharti, Ocular and Stem Cell Translational Research Section, National Eye Institute, NIH

Last updated: March 5, 2021