Analysis of samples was performed at the RPE progenitor stage for two key RPE markers – transcription factor MITF and pigmentation enzyme TYRP1
|
iPSC clone name |
%MITF positive cells |
% TYRP1 positive cells |
1 |
BB0064 CLONE 93 |
97 |
87 |
2 |
BB0152 CLONE 88 |
47 |
56 |
3 |
BB0045 CLONE 86 |
13 |
36 |
4 |
BB00108 CLONE 5 |
96 |
84 |
5 |
BB0038 CLONE 54 |
95 |
22 |
6 |
BB0072 |
NA |
NA |
7 |
BB00125 CLONE 53 |
61 |
69 |
8 |
BB0088 CLONE 22 |
97 |
79 |
9 |
BB00109 CLONE 64 |
78 |
40 |
10 |
BB0066 CLONE 423 |
57 |
66 |
11 |
BB0073 CLONE 13 |
96 |
74 |
Credits: Ruchi Sharma, Devika Bose, Genqing Liang, Roba Dejene, and Kapil Bharti, Ocular and Stem Cell Translational Research Section, National Eye Institute, NIH