Analysis of samples was performed at the RPE progenitor stage for two key RPE markers – transcription factor MITF and pigmentation enzyme TYRP1
| Sample | iPSC clone name | %MITF positive cells | % TYRP1 positive cells |
|---|---|---|---|
| 1 | BB0064 CLONE 93 | 97 | 87 |
| 2 | BB0152 CLONE 88 | 47 | 56 |
| 3 | BB0045 CLONE 86 | 13 | 36 |
| 4 | BB00108 CLONE 5 | 96 | 84 |
| 5 | BB0038 CLONE 54 | 95 | 22 |
| 6 | BB0072 | NA | NA |
| 7 | BB00125 CLONE 53 | 61 | 69 |
| 8 | BB0088 CLONE 22 | 97 | 79 |
| 9 | BB00109 CLONE 64 | 78 | 40 |
| 10 | BB0066 CLONE 423 | 57 | 66 |
| 11 | BB0073 CLONE 13 | 96 | 74 |
Credits: Ruchi Sharma, Devika Bose, Genqing Liang, Roba Dejene, and Kapil Bharti, Ocular and Stem Cell Translational Research Section, National Eye Institute, NIH