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Validation of RPE Differentiation for AREDS2 High-risk iPSC Lines

Analysis of samples was performed at the RPE progenitor stage for two key RPE markers – transcription factor MITF and pigmentation enzyme TYRP1

SampleiPSC clone name%MITF positive cells% TYRP1 positive cells
1BB0064 CLONE 939787
2BB0152 CLONE 884756
3BB0045 CLONE 861336
4BB00108 CLONE 59684
5BB0038 CLONE 549522
6BB0072NANA
7BB00125 CLONE 536169
8BB0088 CLONE 229779
9BB00109 CLONE 647840
10BB0066 CLONE 4235766
11BB0073 CLONE 139674

Credits: Ruchi Sharma, Devika Bose, Genqing Liang, Roba Dejene, and Kapil Bharti, Ocular and Stem Cell Translational Research Section, National Eye Institute, NIH

Last updated: November 25, 2024