Retinal pigment epithelial (RPE) cells stained red by RPE65 antibody.
Retinal pigment epithelial (RPE) cells stained red by RPE65 antibody.

Dr. T. Michael Redmond of the NEI’s Laboratory of Retinal Cell and Molecular Biology, Section on Gene Regulation cloned RPE65, a protein necessary for processing vitamin A in the visual cycle. Genetic mutation in RPE65 causes one type of Leber Congenital Amaurosis (LCA), a group of degenerative diseases of the retina. LCA is the most common cause of congenital blindness in children.  Read more

Last updated: May 1, 2020