34 items
Images of dry AMD retina

NIH researchers discover tooth-enamel protein in eyes with dry AMD

March 13, 2020

A protein that normally deposits mineralized calcium in tooth enamel may also be responsible for calcium deposits in the back of the eye in people with dry age-related macular degeneration (AMD).
Patient undergoes and eye exam. Courtesy National Eye Institute.

For Aging Patients, One Missed Doctor’s Visit Can Lead to Vision Loss

February 6, 2020

Missing a single ophthalmology appointment over a two-year period was associated with decreased visual acuity for patients with macular degeneration according to a new Penn Medicine study.
Brad Gelfand, Ph.D., in the laboratory

Potential Way to Halt Blinding Macular Degeneration Identified

January 22, 2020

Researchers at the University of Virginia have successfully treated age-related macular degeneration (AMD) in mice after finding an unexpected link between the two main forms of the blinding eye disease.
Blood cells are converted into induced pluripotent stem cells, which are them made into retinal pigment epithelial cells (RPE).

NIH launches first U.S. clinical trial of patient-derived stem cell therapy to replace and repair dying cells in retina

December 16, 2019

Researchers at the National Eye Institute (NEI) are launching a clinical trial to test the safety of a novel patient-specific stem cell-based therapy to treat geographic atrophy, the advanced “dry” form of age-related macular degeneration.
Image of scanning electron micrograph

NIH, NIST researchers use artificial intelligence for quality control of stem cell-derived tissues

November 14, 2019

Researchers used artificial intelligence (AI) to evaluate stem cell-derived “patches” of retinal pigment epithelium (RPE) tissue for implanting into the eyes of patients with age-related macular degeneration (AMD), a leading cause of blindness.
Diagram of RPE cell loss

Report: Dry AMD requires broad, systems biology approach leveraging big data, multiple disciplines

July 26, 2019

A large-scale, collaborative, systems biology approach is needed to expedite the discovery of treatments for dry age-related macular degeneration (AMD) – a leading cause of blindness among people 65 and older for which is there is no treatment...
Grantee News

Experimental Drug Delivers One-Two Punch to Vision Loss

April 10, 2019

In studies with lab-grown human cells and in mice, Johns Hopkins Medicine researchers have found that an experimental drug may be twice as good at fighting vision loss as previously thought.
Calcium-rich foods include milk, yogurt and cheese, as well as non-dairy sources such as kale, white beans and sesame seeds.

NIH Study Finds No Evidence That Calcium Increases Risk of AMD

March 21, 2019

Eating a calcium-rich diet or taking calcium supplements does not appear to increase the risk of age-related macular degeneration (AMD), according to the findings of a study by scientists at the National Eye Institute (NEI).

NIH Researchers Hone in on Genes Linked to Age-Related Macular Degeneration

February 11, 2019

National Eye Institute scientists led a collaborative study and zeroed in on genes associated with age-related macular degeneration (AMD), a leading cause of vision loss and blindness among people age 65 and older.
Split panel showing microglia and blood vessels in healthy retina or in retina without TGFβ signaling.

Faulty molecular master switch may contribute to AMD

January 22, 2019

A signaling pathway controlled by transforming growth factor β (TGF-β) could be involved in the progression of age-related macular degeneration (AMD).