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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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NEI funded group finds cell subgroups that may spur retinal cell transplantation success

A new understanding of retinal cell development may help pave the way for future retina transplants, which could restore sight to people whose conditions currently have no effective treatments

NIH research points to new therapeutic opportunities for retinal diseases

NEI scientists have found that the way the retina metabolizes glucose directly controls which genes get switched on and off in light-sensing photoreceptors.

Strategy to prevent age-related macular degeneration identified

A new National Eye Institute-supported study identifies a possible way to slow or block progression of age-related macular degeneration (AMD), a leading cause of blindness in people over age 50.

NIH scientists test in an animal model a surgical technique to improve cell therapy for dry AMD

National Institutes of Health (NIH) scientists have developed a new surgical technique for implanting multiple tissue grafts in the eye's retina. The findings in animals may help advance treatment options for dry age-related macular degeneration.

NIH researchers supercharge ordinary clinical device to get a better look at the back of the eye

Scientists at the National Institutes of Health (NIH) have leveraged artificial intelligence to transform a device designed to see tissues in the back of the eye into one sharp enough to make out individual cells.

NIH researchers develop eye drops that slow vision loss in animals

Researchers at the National Institutes of Health (NIH) have developed eye drops that extend vision in animal models of a group of inherited diseases that lead to progressive vision loss in humans, known as retinitis pigmentosa.
Retinal organoid

Researchers ‘seq’ and find a way to make pig retinal cells to advance eye treatments

Researchers have developed lab-grown pig retinal organoids to test stem cell replacement therapies for diseases that damage the eye's light-sensing photoreceptors.
mouse

New study uncovers how genes influence retinal aging and brain health

Researchers at the Jackson Laboratories used mice with nine different genetic backgrounds to identify factors influencing eye aging, paving the way for eye-based diagnostics for neurodegenerative diseases

NEI study: New take on old marker of cell death

New findings from a National Eye Institute-led study add a twist on how a widely used cell death marker, annexin-V, can be interpreted in the lab and the clinic for tracking retinal cell death in eye diseases such as glaucoma.

UC Irvine-co-led study finds DNA damage is key factor in age-related macular degeneration

Study reveals how DNA damage, a hallmark of aging, compromises the retina’s function and accelerates vision loss. Targeting specific retinal cell types could lead to treatments that slow or stop progression.

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