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University of Maryland School of Medicine study identifies new mechanism that may cause blindness in older adults

April 12, 2021

Using laboratory-grown roundworms as well as human and mouse eye tissue, researchers have identified a new potential mechanism for age-related macular degeneration—the leading cause of blindness among older adults.
Retina model shows RPE cells, choroidal neovascularization-like pathology, vascular layer, PEG layer, Bruch's membrane, drusen

First-ever lab model of human eye offers hope for macular degeneration patients

March 30, 2021

NEI-funded research at the University of Rochester has led to the development of a 3D lab model that mimics the part of the human retina affected in age-related macular degeneration.
Anti-VEGF treatment has greatly improved the prognosis for patients with AMD.

National Eye Institute launches data portal for macular degeneration research

March 17, 2021

The National Eye Institute (NEI) Data Commons now enables researchers to access data from patients with macular degeneration who participated in the Age-related Eye Disease Study 2 (AREDS2).
Rod and cone photoreceptors are shown in greyscale images.

NIH-led team sets new bar in retinal imaging

March 11, 2021

A team led by scientists at the National Eye Institute (NEI) has noninvasively visualized the light-sensing cells in the back of the eye, known as photoreceptors, in greater detail than ever before.

Research points to new hope for treatment-resistant AMD

February 26, 2021

The latest research from the John A. Moran Eye Center reveals how an oxidized form of cholesterol can change choroidal endothelial cells into cells that become scars and may wreak havoc in the eyes of age-related macular degeneration (AMD) patients.

New therapeutic approach may help treat age-related macular degeneration effectively

February 22, 2021

Scientists have found that RUNX1 inhibition presents a new therapeutic approach in the treatment of age-related macular degeneration (AMD), which is the leading cause of blindness in the elderly worldwide.

Breakthrough by Moran Eye Center Scientist, Colleagues Fuels New Line of Disease Research

February 2, 2021

Scientists at the University of Utah have invented a method for synthesizing large enough quantities of very-long-chain polyunsaturated fatty acids (VLC-PUFAs) to evaluate their potential sight-preserving properties.

HIV Drugs May Help Prevent Blinding Macular Degeneration

February 1, 2021

Scientists have identified a group of drugs that may help stop a leading cause of vision loss after making an unexpected discovery that overturns a fundamental belief about DNA.
sugar

Study suggests sugary diet endangers waste-eating protein crucial to cellular repair

January 26, 2021

A protein that functions like the vintage video game Pac-Man, eating toxic cellular waste caused by high sugar intake, is itself compromised by a sugary diet, according to the results of a study in mice with potential implications for humans.

New strategy for treating common retinal diseases shows promise

October 27, 2020

Scientists at Scripps Research have uncovered a potential new strategy for treating eye diseases that affect millions of people around the world, often resulting in blindness.