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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Group of cells tinted purple in the middle and pink at the edges representing a human induced stem cell colony from a patient with albinism.

NIH researchers develop first stem cell model of albinism to study related eye conditions

January 11, 2022

Researchers at the National Eye Institute (NEI) have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA).
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NIH researchers identify potential AMD drugs with stem-cell based research tool

December 15, 2021

Using a stem-cell-derived model, researchers have identified two drug candidates that may slow dry age-related macular degeneration (AMD), a leading cause of blindness for which no treatment exists.
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NIH study traces molecular link from gene to late-onset retinal degeneration

December 9, 2021

Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD), a rare, blinding eye disease.
Scientists in the laboratory

Retinoblastoma resource: Researchers create more accurate research model

August 6, 2021

Scientists at St. Jude Children’s Research Hospital have created a laboratory model for studying retinoblastoma driven by inherited mutations in the RB1 gene.
Anti-VEGF treatment has greatly improved the prognosis for patients with AMD.

National Eye Institute launches data portal for macular degeneration research

March 17, 2021

The National Eye Institute (NEI) Data Commons now enables researchers to access data from patients with macular degeneration who participated in the Age-related Eye Disease Study 2 (AREDS2).

New Research Sheds Light on Vision Loss in Batten Disease

February 5, 2021

New research shows how the mutation associated with Batten disease could potentially lead to degeneration of light sensing photoreceptor cells in the retina, and subsequent vision loss.

Researchers use patients’ cells to test gene therapy for rare eye disease

January 28, 2021

Scientists at the National Eye Institute (NEI) have developed a promising gene therapy strategy for a rare disease that causes severe vision loss in childhood.

Brain Clears the Way for Binocular Vision Even Before Eyes are Open

December 7, 2020

Researchers from Duke University and Cold Spring Harbor Laboratory discovered that chandelier cells are selectively removed from the developing mouse visual cortex even before the animal’s eyes are open.

FAU Researchers receive $1.3 million NIH grant for stem cell research

October 14, 2020

Researchers from Florida Atlantic University’s Schmidt College of Medicine hope to conquer a major limitation in the ability for scientists to engineer tissues for regenerative therapies for age-related and degenerative diseases.
NEI Audacious Goals Initiative for regenerative medicine in vision identity mark

Eye institute’s audacious quest: What once was lost might now be regrown

October 13, 2020

The National Eye Institute (NEI) Audacious Goals Initiative (AGI) is exploring the possibility that the natural world holds the keys to restorative therapies that might unlock regenerative powers in humans.