15 items

NIH, NIST researchers use artificial intelligence for quality control of stem cell-derived tissues

November 14, 2019

Researchers used artificial intelligence (AI) to evaluate stem cell-derived “patches” of retinal pigment epithelium (RPE) tissue for implanting into the eyes of patients with age-related macular degeneration (AMD), a leading cause of blindness.

A Road Map to Stem Cell Development

May 22, 2019

Johns Hopkins Medicine researchers report they have created a method of mapping how the central nervous system develops by tracking the genes expressed in cells.

IUPUI researchers re-create retinal microenvironment in a dish with human stem cells

January 24, 2019

IUPUI scientists have used retinal ganglion cells derived from human pluripotent stem cells to create models that better mimic the human retina.

NIH researchers rescue photoreceptors, prevent blindness in animal models of retinal degeneration

January 16, 2019

Using a novel patient-specific stem cell-based therapy, researchers at the National Eye Institute (NEI) prevented blindness in animal models of geographic atrophy, the advanced “dry” form of age-related macular degeneration (AMD)...

NIH researchers discover neural code that predicts behavior

November 26, 2018

Scientists at the National Eye Institute (NEI) have found that neurons in the superior colliculus, an ancient midbrain structure found in all vertebrates, are key players in allowing us to detect visual objects and events.

IUPUI biologists use ‘mini retinas’ to better understand connection between eye and brain

October 25, 2018

Researchers at Indiana University develop 3D mini retinas, which they will use to study retinal ganglion cells. Retinal ganglion cells are nerves that transmit information from the eye to the brain.

NIH discovery brings stem cell therapy for eye disease closer to the clinic

January 2, 2018

Scientists at the National Eye Institute (NEI) report that tiny tube-like protrusions called primary cilia on cells of the retinal pigment epithelium (RPE) are essential for the survival of the retina’s light-sensing photoreceptors.

Stem cell secretions may protect against glaucoma

January 26, 2017

A new study in rats shows that stem cell secretions, called exosomes, appear to protect cells in the retina, the light-sensitive tissue in the back of the eye.

CRISPR Used to Repair Blindness-causing Genetic Defect in Patient-derived Stem Cells

January 27, 2016

Columbia University Medical Center (CUMC) and University of Iowa scientists have used a new gene-editing technology called CRISPR to repair a genetic mutation responsible for retinitis pigmentosa (RP), an inherited condition

Stem Cell Injection May Soon Reverse Vision Loss Caused By Age-Related Macular Degeneration

April 15, 2015

An injection of stem cells into the eye may soon slow or reverse the effects of early-stage age-related macular degeneration, according to new research from scientists at Cedars-Sinai.