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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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45 items
Photoreceptor precursors

Progress toward a stem cell–based therapy for blindness

julio 28, 2022

A multi-institutional effort led by researchers at the UPenn School of Veterinary Medicine is taking steps to develop an effective technique to regenerate photoreceptors cells and restore sight in people with vision disorders.
NEI AGI audacious Goals Initiative for Regenerative Medicine

NEI's regenerative medicine initiative making progress toward its audacious goal

julio 5, 2022

A new report outlines progress toward the National Eye Institute's Audacious Goals Initiative (AGI), an effort to restore vision through research in regenerative medicine. The report, published in Nature Medicine.
Multicolored image of photoreceptors and their long connecting processes, called axons, within a stem cell-derived retinal organoid

U. Wisconsin eye research uncovers how stem cell photoreceptors reach their targets

junio 15, 2022

A new study reveals how photoreceptors grown from stem cells might extend biological wires, known as axons, to contact existing neurons.
retina blood vessels

Indiana University-led study shows human induced pluripotent stem cells improve visual acuity, vascular health

marzo 17, 2022

Researchers improved vision in a type 2 diabetes mouse model by reprogramming blood cells into endothelial cells with vessel reparative properties similar to endothelial colony forming cells.
Cone photoreceptors from retinal organoids

UW study finds photoreceptor cells from retinal organoids can replicate key function of vision

febrero 2, 2022

Researchers from the U. of Wisconsin have shown that a retinal cell type derived from human pluripotent stem cells is capable of the complex process of detecting light and converting that signal to electrical waves.
Group of cells tinted purple in the middle and pink at the edges representing a human induced stem cell colony from a patient with albinism.

NIH researchers develop first stem cell model of albinism to study related eye conditions

enero 11, 2022

Researchers at the National Eye Institute (NEI) have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA).
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NIH researchers identify potential AMD drugs with stem-cell based research tool

diciembre 15, 2021

Using a stem-cell-derived model, researchers have identified two drug candidates that may slow dry age-related macular degeneration (AMD), a leading cause of blindness for which no treatment exists.
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NIH study traces molecular link from gene to late-onset retinal degeneration

diciembre 9, 2021

Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD), a rare, blinding eye disease.
Scientists in the laboratory

Retinoblastoma resource: Researchers create more accurate research model

agosto 6, 2021

Scientists at St. Jude Children’s Research Hospital have created a laboratory model for studying retinoblastoma driven by inherited mutations in the RB1 gene.
Anti-VEGF treatment has greatly improved the prognosis for patients with AMD.

National Eye Institute launches data portal for macular degeneration research

marzo 17, 2021

The National Eye Institute (NEI) Data Commons now enables researchers to access data from patients with macular degeneration who participated in the Age-related Eye Disease Study 2 (AREDS2).