Increased levels of RBP3 both protects against and treats diabetic retinopathy
July 3, 2019
Diabetic Eye Disease
Genetics
Translational Research
Grantee
Researchers at Joslin Diabetes Center have shown that a protein found in the eye can protect against and potentially treat diabetic eye disease. At high enough levels, Retinol Binding Protein 3 (or RBP3) prevents the development of diabetic retinopathy. If introduced early enough in the development of the disease, RBP3 was shown to reverse the effects of the complication in rodent models of diabetes.