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MSU researchers discover link between cholesterol and diabetic retinopathy

September 5, 2023
Diabetic Eye Disease Retina
Translational Research
Grantee

Advancements that could lead to earlier diagnosis and treatment for diabetic retinopathy, a common complication that affects the eyes, have been identified by a multi-department research team from Michigan State and other universities.

Their findings were recently published in Diabetologia, the official journal of the European Association for the Study of Diabetes. Additional contributors are from the University of Alabama at Birmingham, Case Western Reserve University and Western University of Health Sciences. The study was funded by the National Eye Institute.

Researchers found that diabetes, age-related health conditions and other metabolic disorders can lead to a buildup of cholesterol in the retina. This tends to crystalize and contribute to the development of diabetic retinopathy.

Crystalized deposits are very reflective and can be seen in images of the retina. This is important because noninvasive retina evaluations can be done by most optometrists, creating an opportunity for earlier diagnosis for more people.