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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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472 items

Eye cells "rewire" themselves when vision begins to fail

A new study funded by the National Eye Institute shows that certain retinal cells can rewire themselves when vision begins to deteriorate in retinitis pigmentosa, a genetic eye disease that leads to progressive blindness.

Strategy to prevent age-related macular degeneration identified

A new National Eye Institute-supported study identifies a possible way to slow or block progression of age-related macular degeneration (AMD), a leading cause of blindness in people over age 50.

NIH researchers identify brain circuits responsible for visual acuity

Researchers at the National Institutes of Health (NIH) have identified which brain circuits are vital for visual acuity and how they are affected by damaged retinal cells.

NEI-funded researchers test new visual prosthesis system to restore vision

Brown University researchers have identified a promising new approach that may help to restore vision in people affected by macular degeneration and other retinal disorders.

Repurposing a high blood pressure drug may prevent vision loss in inherited blinding diseases

New studies in rats suggest the drug reserpine, approved in 1955 for high blood pressure, might treat the blinding disease retinitis pigmentosa. No therapy exists for this rare inherited disease, which starts affecting vision from childhood.
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NEI-funded researchers “push the ENVLPE” with new virus-like particle to fix mutations causing blindness

New CRISPR gene editing approach may also be useful for treating other inherited diseases, such as cystic fibrosis and familial hypercholesterolemia
Retinal organoid

Researchers ‘seq’ and find a way to make pig retinal cells to advance eye treatments

Researchers have developed lab-grown pig retinal organoids to test stem cell replacement therapies for diseases that damage the eye's light-sensing photoreceptors.
eye with herpes stromal keratitis

Wayne State researchers find potential mechanism to protect against infection-induced vision impairment

Herpes stromal keratitis is a debilitating vision condition that occurs in response to a herpes infection in the eye.
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Mount Sinai-led research team identifies underlying mechanisms of age-related dysfunction in glands crucial to eye function

A team led by researchers at Mount Sinai has identified in mice a potential therapeutic target for dry eye disease.
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New study uncovers how genes influence retinal aging and brain health

Researchers at the Jackson Laboratories used mice with nine different genetic backgrounds to identify factors influencing eye aging, paving the way for eye-based diagnostics for neurodegenerative diseases