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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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NIH challenge prize winners propose innovative use of open-science collaborative to advance eye health

Four teams have won a prize competition aimed at integrating eye care and ocular imaging data into studies using large healthcare datasets in biomedical research.

NIH researchers supercharge ordinary clinical device to get a better look at the back of the eye

Scientists at the National Institutes of Health (NIH) have leveraged artificial intelligence to transform a device designed to see tissues in the back of the eye into one sharp enough to make out individual cells.

Repurposing a high blood pressure drug may prevent vision loss in inherited blinding diseases

New studies in rats suggest the drug reserpine, approved in 1955 for high blood pressure, might treat the blinding disease retinitis pigmentosa. No therapy exists for this rare inherited disease, which starts affecting vision from childhood.

NIH researchers develop eye drops that slow vision loss in animals

Researchers at the National Institutes of Health (NIH) have developed eye drops that extend vision in animal models of a group of inherited diseases that lead to progressive vision loss in humans, known as retinitis pigmentosa.
Doctor examines child's eye with a slit lamp.

Treatment pause leads to high rate of relapse in children with a type of autoimmune eye inflammation

According to a National Institutes of Health (NIH)-funded clinical study, children with a type of autoimmune arthritis and associated eye inflammation are likely to experience disease recurrence when discontinuing a biologic therapy called adalimumab.
A myopic eye grows too long from front to back. Light gets focused in front of the retina. Single-vision contact lenses focus distance vision on the retina, but peripheral light is focused behind the retina. Multifocal contact lenses focus distance vision on the retina and peripheral light in front of the retina, signaling the eye to slow growth.Multifocal contact lenses are concentric circles consisting of an add power treatment zone in the outer rings that focuses peripheral rays in front of the retina.

Contact lenses used to slow nearsightedness in youth have a lasting effect

In a follow up study, researchers found that children who wore special contact lenses to slow progression of myopia maintained the treatment benefit even after they stopped wearing the contacts as older teens.
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NEI launches video contest to inspire teens to explore science

Annual Eye on the Future Teen Video Contest inspires high school students from all backgrounds to explore science. Winners receive $2,000 and a trip to NIH.
Extracellular vesicle

Report on extracellular vesicles

A new report summarizes proceedings from an NEI workshop on extracellular vesicles (Evs) – cell-secreted nanoparticles that mediate cell-cell communication.

NEI study: New take on old marker of cell death

New findings from a National Eye Institute-led study add a twist on how a widely used cell death marker, annexin-V, can be interpreted in the lab and the clinic for tracking retinal cell death in eye diseases such as glaucoma.

NIH-led scientific team defines elements of brain-based visual impairment in children

Experts convened by the National Institutes of Health (NIH) have identified five elements of a brain-based condition that has emerged as a leading cause of vision impairment starting in childhood in the United States and other industrialized nations.