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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Congressman Pete Sessions visits NIH

Texas Congressman Pete Sessions visited the NIH March 27 to meet with NEI Director Michael F. Chiang, M.D., and to tour NEI’s Section on Ocular and Stem Cell Translational Research, led by Kapil Bharti, Ph.D.
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FDA-approved drug shows promise in lab models for blinding childhood disease 

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10).
Rods and Cones image

Early study shows cones in retinal degeneration, thought to be dormant, may retain visual function

New UCLA research in mice suggests that “dormant” cone photoreceptors in the degenerating retina are not dormant at all, but continue to function, producing responses to light and driving retinal activity for vision.
Nanoparticle. Courtesy of Biorender.

Tiny nanoparticle could have big impact on patients receiving corneal transplants

Using nanoparticles to encapsulate eye medication decreased graft rejection while requiring fewer and smaller doses.
Views of a patio from a walking, crawling, or flying perspective, and a collection of scrambled views.

Visually navigating on foot uses unique brain region

Using vision to efficiently move through an area by foot uses a unique region of the brain’s cortex, according to a small study funded by the National Eye Institute (NEI).

Researchers discover therapeutic target to aid in glaucoma treatment

Indiana University researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma.
Fundus photograph of age-related macular degeneration showing drusen.

Discovery suggests new way to prevent common causes of vision loss

UVA Health scientists have discovered an unknown contributor to harmful blood vessel growth in the eye that could lead to new treatments for blinding macular degeneration and other common causes of vision loss.

HSC researcher discovered a potential cause for keratoconus

Researchers at the University of North Texas Health Science Center are the first to characterize extracellular vesicles in the tears of patients with keratoconus.
Synapses between neurons in thalamus and cortex.

Sparse, small, but diverse neural connections help make perception reliable, efficient

In a study from the Picower Institute at MIT, the first detailed mapping and modeling of thalamus inputs onto visual cortex neurons show brain leverages “wisdom of the crowd” to process sensory information.

Small creatures teach big lessons

In the vision field, researchers turn to a variety of small, non-mammalian animal models to help bridge gaps in our scientific knowledge.