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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Photoreceptor degeneration tied to lipofuscin accumulation.

Advancing a treatment for a common eye disease that lacks one

The road from discovering a potential drug to getting the therapy into the hands of patients is a long and uncertain one. An NIH program called Blueprint Neurotherapeutics Network helps basic researchers prep for clinical trials and regulatory approval.
Three soccer players on a field. Center player looks down at the ball by her feet.

Attention to objects in peripheral vision is not driven by tiny eye movements

New research by National Eye Institute (NEI) investigators shows that while microsaccades seem to boost or diminish the strength of the brain signals underlying attention, eye movements are not drivers of those brain signals.
screen shot of a Zoom meeting

NEI hosts international strategic planning meeting

The digital summit of global partners in vision research discussed opportunities for collaboration.

Vision scientists discover new angle on path of light through photoreceptors

Researchers at the National Eye Institute (NEI) have discovered that power-producing organelles in the eye’s photoreceptor cells, called mitochondria, function as microlenses that help channel light to these cells’ outer segments.
Green iris

Report on anterior segment inflammation and immunity posted

Part of the Anterior Segment Initiative, the meeting addressed gaps in knowledge, barriers to new therapies, and promising areas for research.

NIH study classifies vision loss and retinal changes in Stargardt disease

National Eye Institute researchers developed and validated an artificial-intelligence-based method to evaluate patients with Stargardt, an eye disease that can lead to childhood vision loss.
Man with patch over his eye.

Cataract surgery does not cause disease progression in people with AMD

People with age-related macular degeneration (AMD) can undergo cataract surgery without fear of worsening their disease.

NIH researchers identify potential AMD drugs with stem-cell based research tool

Using a stem-cell-derived model, researchers have identified two drug candidates that may slow dry age-related macular degeneration (AMD), a leading cause of blindness for which no treatment exists.

NIH study traces molecular link from gene to late-onset retinal degeneration

Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD), a rare, blinding eye disease.
Mouse retina

NIH scientists discover new B cell that tempers autoimmunity

Findings in mice point to potential therapies for blinding eye disease uveitis and multiple sclerosis