NEI Research News

A new study shows that deleting one of the inhibitors of the RPE65 gene in a mouse model that carries a human disease mutation prevents degeneration of cone photoreceptors that are used for daytime high-resolution color vision.

Scientists at Scripps Research have uncovered a potential new strategy for treating eye diseases that affect millions of people around the world, often resulting in blindness.

A newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells using gene therapy.

The National Eye Institute (NEI) Audacious Goals Initiative (AGI) is exploring the possibility that the natural world holds the keys to restorative therapies that might unlock regenerative powers in humans.

Oklahoma Medical Research Foundation scientists have identified a compound that could give birth to therapies for a host of eye diseases that include retinopathy of prematurity and diabetic retinopathy.

NEI-funded scientists are hacking the zebrafish’s innate regenerative capacity to learn how to treat human disease.

New research from the University of Utah provides insight on how people with retinal degenerative disease can maintain their night vision for a relatively long period of time.

The brain’s visual centers must be adept at filtering out noise from retinal cells to get to the true signal, and those filters have to constantly adapt. Prosthetic retinas are going to need this same filtering to succeed, NEI-funded research shows.

Researchers funded by the National Eye Institute show in a mammalian model the reprogramming of heritability to promote disease resilience in the next generation.

Scientists at the University of Washington School of Medicine detect minute changes in response to light in photoreceptors in a living eye.