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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Multiphoton images show the outer segments of cone and rod photoreceptor cells in 215-day retinal organoids. Immunostaining shows a marker for cones (green) and rods (red). The “A” view shows optical sections; “B” is a reconstructed three-dimensional view.

NEI Awards Prize for Progress Toward Developing Lab-Made Retinas

The National Eye Institute (NEI) awarded $25,000 to a team led by Wei Liu, Ph.D., Albert Einstein College of Medicine, for demonstrating progress toward the development of a living model of the human retina...
Images show multimodal technique using adaptive optics and angiography to simultaneously see photoreceptors (left), retinal pigment epithelial cells (center), and choriocapillaris in the living human eye.

NIH scientists combine technologies to view the retina in unprecedented detail

By combining two imaging modalities—adaptive optics and angiography—investigators at the National Eye Institute (NEI) can see live neurons, epithelial cells, and blood vessels deep in the eye’s light-sensing retina.
NEI Audacious Goals Initiative for regenerative medicine in vision identity mark

Five research teams will develop new models for eye disease research

The National Eye Institute (NEI), part of the National Institutes of Health, has awarded grants to five multi-disciplinary teams to develop new disease models for a range of eye conditions.
Grantee News

Handheld Probe Images Photoreceptors in Children

Portable probe developed by Duke biomedical engineers makes it possible to capture images of photoreceptors in the eyes of young children.
Illustration of icosahedral virus capsid, containing circular AAV vector. Arrows point from green and blue colored regions of the vector to shRNA and rhodopsin protein, respectively.

Researchers find potential new gene therapy for blinding disease

Scientists funded by the National Eye Institute (NEI) report a novel gene therapy that halts vision loss in a canine model of a blinding condition called autosomal dominant retinitis pigmentosa (adRP).
Artistic image shows Müller glia-derived rod photoreceptors.

NIH-funded researchers reverse congenital blindness in mice

Researchers funded by the National Eye Institute (NEI) have reversed congenital blindness in mice by changing supportive cells in the retina called Müller glia into rod photoreceptors.
Grantee News

Study suggests glaucoma may be an autoimmune disease

Research from MIT and Massachusetts Eye and Ear points to an autoimmune response as the driver of optic nerve damage in a mouse model of glaucoma.
James Golladay and Aman George hold up grant award check

Knights Templar Eye Foundation awards research grant to NEI scientist

National Eye Institute (NEI) Postdoctoral Fellow Aman George, Ph.D., has received a $65,000 grant from the Knights Templar Eye Foundation to identify new drug treatments for vision impairment in children with a type of albinism.
Ground squirrel curled up in a nest

NIH researchers develop 'hibernation in a dish' to study how animals adapt to the cold

Researchers at the National Eye Institute have discovered cellular mechanisms that help the 13-lined ground squirrel survive hibernation.
Retina organoids mimic the structure and function of the human retina to serve as a platform to study underlying causes of retinal diseases, test new drug therapies, and provide a source of cells for transplantation. credit: David Gamm, M.D., Ph.D., University of Wisconsin-Madison

NIH solicits next-generation retina organoids in prize competition

A competition for radical ideas in the fight against blindness will move to its next phase by challenging participants to build functioning human retina prototypes.