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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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James W. Gollady, Jr., Right Eminent Department Commander (right), presents Hotaling with a check from the Knights Templar Eye Foundation. “I think this award is extremely important to pave a pathway for me in medical research,” said Hotaling.  (Joe Balintfy, NEI)

NEI Scientist Receives Research Grant from Knights Templar Eye Foundation

NEI research fellow Nathan Hotaling, PhD, has been awarded a $65,000 grant from the Knights Templar Eye Foundation to develop a stem cell-based system to study Best disease, a genetic disorder that can cause progressive vision loss.
Grantee News

Pain medicine helps preserve vision in model of inherited retinal degeneration

A pain medicine that potently activates a receptor vital to a healthy retina appears to help preserve vision in an animal model of severe retinal degeneration, NEI-funded scientists at Medical College of Georgia at Augusta University report.
Rods and Cones image

NIH Vision Scientists Test Theory of How Rods in our Retina Originated

Retinas from our earliest vertebrate ancestors had cone-like photoreceptors, presumably allowing them to see in daylight, but little ability to see at night.
Dr. Emily Chew of the National Eye Institute examines a patient’s eyes. Photo credit: National Eye Institute.

Eye Study Underscores the Long-lasting Benefits of Controlling Diabetes

People with type 2 diabetes who intensively controlled their blood sugar level were found to have cut their risk of diabetic retinopathy in half.
Patient undergoes and eye exam. Courtesy National Eye Institute.

Age-related macular degeneration before and after the era of anti-VEGF drugs

In a study of nearly 650 people with the eye disease age-related macular degeneration (AMD), half still had vision 20/40 or better after five years of treatment with anti-VEGF drugs that are injected into the eye.
May is Healthy Vision Month which is not just about seeing an Eye Chart

May is Healthy Vision Month

David Watson has worn glasses to correct nearsightedness the majority of his life, and had his vision checked regularly to make sure his prescription was up to date.
Grantee News

Before Retinal Cells Die, They Regenerate, Penn Vet Blindness Study Finds

Researchers at the University of Pennsylvania showed that in a form of canine blindness retinal cells continue to differentiate for a period of time early in a dog’s life before overwhelming cell death caused the retina to degenerate.
Grantee News

Discovery Identifies New RX Target for Age-related Macular Degeneration & Alzheimer's

Researchers at LSU Health New Orleans have shown that a protein critical to the body’s ability to remove waste products from the brain and retina is diminished in age-related macular degeneration.
Patient undergoes and eye exam. Courtesy National Eye Institute.

Eylea Outperforms Avastin for Diabetic Macular Edema with Moderate or Worse Vision Loss

A two-year clinical trial that compared three drugs for diabetic macular edema (DME) found that gains in vision were greater for participants receiving the drug Eylea (aflibercept) than for those receiving Avastin (bevacizumab).
The researchers developed a technique to study live cells in patches of retina, shown here by confocal microscopy. After 2 hours, the vast majority of the cells are alive (green); only a few cells at the perimeter have died (stained red with a dye).

Retinal Cells Work with Little Reserve Energy; May Explain Vulnerability to Eye Diseases

Our eyes are especially demanding when it comes to energy: Along with our brain, they require a substantial amount of power to keep them functioning and healthy.